Evidence map›Paper›PMID 39405011›Full record

ArticleJournal of echocardiography2025

Strain rate during isovolumic relaxation as a prognostic biomarker for long-term cardiovascular morbidity and mortality: an exploratory study on a general population.

Konstantina Papangelopoulou, Tatiana Kuznetsova, Marta Orlowska, Nicholas Cauwenberghs, Jens-Uwe Voigt, Jan D'hooge

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Article in Journal of echocardiography, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Konstantina PapangelopoulouDepartment of Cardiovascular Sciences, Katholieke Universiteit Leuven, Oude Markt 13, 3000, Louvain, Belgium. konstantina.papangelopoulou@kuleuven.com.ORCID http://orcid.org/0000-0003-4159-0177
Tatiana KuznetsovaDepartment of Cardiovascular Sciences, Katholieke Universiteit Leuven, Oude Markt 13, 3000, Louvain, Belgium.
Marta OrlowskaDepartment of Cardiovascular Sciences, Katholieke Universiteit Leuven, Oude Markt 13, 3000, Louvain, Belgium.
Nicholas CauwenberghsDepartment of Cardiovascular Sciences, Katholieke Universiteit Leuven, Oude Markt 13, 3000, Louvain, Belgium.
Jens-Uwe VoigtDepartment of Cardiovascular Sciences, Katholieke Universiteit Leuven, Oude Markt 13, 3000, Louvain, Belgium.
Jan D'hoogeDepartment of Cardiovascular Sciences, Katholieke Universiteit Leuven, Oude Markt 13, 3000, Louvain, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsLeft ventricular (LV) strain rate (SR) during early relaxation correlates with LV filling pressures and has been assessed as a prognostic biomarker in several cardiac diseases. Conversely, even though LV SR during isovolumic relaxation (SR

methods657 subjects (mean age 51.6y; 47.6% males) were included in this study and, besides clinical and standard echocardiographic assessment, tissue Doppler imaging (TDI)-based SR was measured during IVR (SR

resultsDuring the follow-up period (median 12.1 years), the total number of major adverse cardiac events was 85 (13.4%). Overall, after adjustment for known cardiovascular risk factors and important echocardiographic indices in a multivariable-adjusted Cox regression model, SR

conclusionSR

Indexed as

Cardiovascular DiseasesEchocardiography, DopplerHeart VentriclesMyocardial ContractionVentricular Function, LeftAdultAgedBiomarkersDiastoleFemaleFollow-Up StudiesHumansMaleMiddle AgedMorbidityPrognosisBiomarkersEchocardiographyGeneral populationIsovolumic relaxationStrain rateSurvival analysis

Identifiers

PMID39405011

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.