Evidence map›Paper›PMID 39406965›Full record

ReviewInternal and emergency medicine2025

Deprescribing strategies in older patients with heart failure.

Gregorio Tersalvi, Vittorio Beltrani, Marco Peronti, Ludovico Furlan, Andrew Foy, Luigi Biasco

Abstract readReview
PubMed Publisher
In one paragraph

Review in Internal and emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Deprescribing: Reducing Harm, Enhancing Care.Rambam Maimonides medical journal · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gregorio TersalviDepartment of Internal Medicine, Ente Ospedaliero Cantonale, Mendrisio, Switzerland. tersalvi@gmail.com.ORCID 0000-0003-1845-1777
Vittorio BeltraniDepartment of Internal Medicine, Ente Ospedaliero Cantonale, Mendrisio, Switzerland.
Marco PerontiDivision of Geriatrics, Ente Ospedaliero Cantonale, Mendrisio, Switzerland.
Ludovico FurlanDepartment of Internal Medicine, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
Andrew FoyDivision of Cardiology, Penn State Milton S. Hershey Medical Center, Hershey, PA, USA.
Luigi BiascoDepartment of Biomedical Sciences, University of Italian Switzerland, Lugano, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Older patients with heart failure are particularly vulnerable due to a wide range of associated comorbidities, disability, and frailty. This population often receives multiple prescriptions, increasing the risk of adverse drug reactions, non-adherence, and drug interactions. Deprescribing, which involves reducing the number of medications to the lowest clinically reasonable limit, has the potential to decrease the risk of drug interactions and enhance patients' quality of life. Moreover, simplifying medication regimens may improve adherence to essential heart failure therapies. This scientific review aims to comprehensively examine deprescribing strategies in older patients with heart failure. It explores the rationale, challenges, benefits, and potential approaches to optimizing medication regimens in this vulnerable population. Furthermore, the review suggests a practical, step-by-step approach for performing deprescribing in older patients with heart failure.

Indexed as

DeprescriptionsHeart FailureAgedAged, 80 and overHumansPolypharmacyCompeting riskDrug interactionsFrailtyMedication simplificationPolypharmacy

Identifiers

PMID39406965

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.