Evidence map›Paper›PMID 39407583›Full record

ArticleMolecules (Basel, Switzerland)2024

1,2,4-Oxadiazole Derivatives: Physicochemical Properties, Antileishmanial Potential, Docking and Molecular Dynamic Simulations of

Deyzi C S Barbosa, Vanderlan N Holanda, Elton M A Lima, Marton K A Cavalcante, Maria Carolina A Brelaz-de-Castro, Elton J F Chaves, Gerd B Rocha, Carla J O Silva, Ronaldo N Oliveira, Regina C B Q Figueiredo

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Deyzi C S BarbosaDepartment of Microbiology, Aggeu Magalhães Institute (IAM-FIOCRUZ), Recife 50740-465, PE, Brazil.ORCID 0000-0002-9026-6528
Vanderlan N HolandaDepartment of Biomedicine, University Center of Vitória de Santo Antão (UNIVISA), Vitória de Santo Antão 55610-050, PE, Brazil.ORCID 0000-0001-5309-0036
Elton M A LimaCenter for Exact and Natural Sciences, Federal University of Pernambuco (UFPE), Recife 50740-560, PE, Brazil.ORCID 0000-0003-0545-2447
Marton K A CavalcanteParasitology Laboratory, Academic Center of Vitória, Federal University of Pernambuco (UFPE), Recife 50670-420, PE, Brazil.ORCID 0000-0001-9995-7352
Maria Carolina A Brelaz-de-CastroParasitology Laboratory, Academic Center of Vitória, Federal University of Pernambuco (UFPE), Recife 50670-420, PE, Brazil.ORCID 0000-0003-2205-0618
Elton J F ChavesDepartment of Chemistry, Federal University of Paraíba (UFPB), João Pessoa 58051-900, PB, Brazil.ORCID 0000-0001-8573-2216
Gerd B RochaDepartment of Chemistry, Federal University of Paraíba (UFPB), João Pessoa 58051-900, PB, Brazil.ORCID 0000-0001-9805-9497
Carla J O SilvaDepartment of Fundamental Chemistry, Federal University of Pernambuco (UFPE), Recife 50740-540, PE, Brazil.ORCID 0000-0002-0215-755X
Ronaldo N OliveiraDepartment of Chemistry, Federal Rural University of Pernambuco (UFRPE), Recife 52171-900, PE, Brazil.ORCID 0000-0002-6111-2351
Regina C B Q FigueiredoDepartment of Microbiology, Aggeu Magalhães Institute (IAM-FIOCRUZ), Recife 50740-465, PE, Brazil.ORCID 0000-0001-5806-0944

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Visceral leishmaniasis (VL), caused by protozoa of the genus

Indexed as

Antiprotozoal AgentsLeishmania infantumMolecular Docking SimulationMolecular Dynamics SimulationOxadiazolesProtozoan ProteinsAnimalsCell LineLeishmaniasis, VisceralMembrane Potential, MitochondrialMiceAntiprotozoal AgentsOxadiazolesProtozoan Proteins1,2,4-oxadiazolechemotherapymolecular dockingmolecular dynamicultrastructurevisceral leishmaniasis

Identifiers

PMID39407583
PMCPMC11478322

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.