Evidence map›Paper›PMID 39407623›Full record

ReviewMolecules (Basel, Switzerland)2024

Bioactive Potential of Algae and Algae-Derived Compounds: Focus on Anti-Inflammatory, Antimicrobial, and Antioxidant Effects.

Maima Matin, Magdalena Koszarska, Atanas G Atanasov, Karolina Król-Szmajda, Artur Jóźwik, Adrian Stelmasiak, Monika Hejna

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Fucoidan-Mediated Biogenic Gold Nanoparticles fromPharmaceuticals (Basel, Switzerland) · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Proangiogenic and Collagen-Promoting Effects of a 70% Ethanol Extract ofInternational journal of molecular sciences · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Role ofMarine drugs · 2025
    Article
  20. Microalgae: revolutionizing skin repair and enhancement.Biotechnology reports (Amsterdam, Netherlands) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maima MatinDepartment of Biotechnology and Nutrigenomics, Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences, 05-552 Jastrzębiec, Poland.ORCID 0009-0001-5388-6285
Magdalena KoszarskaDepartment of Biotechnology and Nutrigenomics, Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences, 05-552 Jastrzębiec, Poland.ORCID 0000-0002-0442-6127
Atanas G AtanasovDepartment of Biotechnology and Nutrigenomics, Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences, 05-552 Jastrzębiec, Poland.ORCID 0000-0003-2545-0967
Karolina Król-SzmajdaDepartment of Biotechnology and Nutrigenomics, Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences, 05-552 Jastrzębiec, Poland.
Artur JóźwikDepartment of Biotechnology and Nutrigenomics, Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences, 05-552 Jastrzębiec, Poland.ORCID 0000-0001-5546-9891
Adrian StelmasiakDepartment of Technique and Food Development, Institute of Human Nutrition Sciences, University of Life Sciences of Warsaw, 02-787 Warsaw, Poland.
Monika HejnaDepartment of Biotechnology and Nutrigenomics, Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences, 05-552 Jastrzębiec, Poland.ORCID 0000-0003-3427-9831

Funding

European Union's Horizon 2020 Research and Innovation Programme under the Marie Skłodowska-Curie grant agreement and from the Polish Ministry of Education and Science. 847639
6 · The paper itself

Abstract

Algae, both micro- and macroalgae, are recognized for their rich repository of bioactive compounds with potential therapeutic applications. These marine organisms produce a variety of secondary metabolites that exhibit significant anti-inflammatory, antioxidant, and antimicrobial properties, offering promising avenues for the development of new drugs and nutraceuticals. Algae-derived compounds, including polyphenols, carotenoids, lipids, and polysaccharides, have demonstrated efficacy in modulating key inflammatory pathways, reducing oxidative stress, and inhibiting microbial growth. At the molecular level, these compounds influence macrophage activity, suppress the production of pro-inflammatory cytokines, and regulate apoptotic processes. Studies have shown that algae extracts can inhibit inflammatory signaling pathways such as NF-κB and MAPK, reduce oxidative damage by activating Nrf2, and offer an alternative to traditional antibiotics by combatting bacterial infections. Furthermore, algae's therapeutic potential extends to addressing diseases such as cardiovascular disorders, neurodegenerative conditions, and cancer, with ongoing research exploring their efficacy in preclinical animal models. The pig model, due to its physiological similarities to humans, is highlighted as particularly suitable for validating the bioactivities of algal compounds in vivo. This review underscores the need for further investigation into the specific mechanisms of action and clinical applications of algae-derived biomolecules.

Indexed as

Anti-Infective AgentsAnti-Inflammatory AgentsAntioxidantsSeaweedAnimalsHumansMicroalgaeOxidative StressAnti-Infective AgentsAnti-Inflammatory AgentsAntioxidantsanti-inflammatoryantimicrobialantioxidantbioactive compoundsmicro and macroalgaetherapeutic applications

Identifiers

PMID39407623
PMCPMC11477577

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.