Evidence map›Paper›PMID 39408298›Full record

Trial reportNutrients2024

The Physiological and Performance Effects of Actovegin during Maximal Cardiopulmonary Exercise Testing: A Randomized, Double-Blind, Placebo-Controlled Trial.

Dragana Milovanović, Dragan Radovanović, Vladimir Živković, Ivan Srejović, Miloš Glišić, Vladimir Jakovljević, Aaron Scanlan, Nenad Ponorac, Emilija Stojanović

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dragana MilovanovićMilitary Medical Academy, 11000 Belgrade, Serbia.ORCID 0009-0008-8879-5923
Dragan RadovanovićFaculty of Sport and Physical Education, University of Niš, 18000 Niš, Serbia.ORCID 0000-0002-1690-2127
Vladimir ŽivkovićFaculty of Medical Sciences, Department of Physiology, University of Kragujevac, 34000 Kragujevac, Serbia.
Ivan SrejovićFaculty of Medical Sciences, Department of Physiology, University of Kragujevac, 34000 Kragujevac, Serbia.ORCID 0000-0002-3835-1856
Miloš GlišićFaculty of Medical Sciences, Department of Physiology, University of Kragujevac, 34000 Kragujevac, Serbia.
Vladimir JakovljevićFaculty of Medical Sciences, Department of Physiology, University of Kragujevac, 34000 Kragujevac, Serbia.ORCID 0000-0002-0071-8376
Aaron ScanlanSchool of Health, Medical and Applied Sciences, Central Queensland University, Rockhampton 4701, Australia.ORCID 0000-0002-0750-8697
Nenad PonoracFaculty of Medicine, Department of Physiology, University of Banja Luka, 78101 Banja Luka, Bosnia and Herzegovina.
Emilija StojanovićFaculty of Medical Sciences, Department of Physiology, University of Kragujevac, 34000 Kragujevac, Serbia.ORCID 0000-0001-7481-0629

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEvidence regarding the performance-related effects of Actovegin is limited, despite legislated restrictions being in place for this supplement within sport settings.

objectivesOur study examined the effects of Actovegin on physiological responses and performance during maximal cardiopulmonary exercise in collegiate athletes.

methodsA randomized, double-blind, placebo-controlled experimental design was adopted. Moderately trained collegiate athletes from various sports were randomly allocated to placebo (

resultsA significant time * group effect (

conclusionsOur findings suggest that although physiological and performance alterations were evident with Actovegin supplementation during cardiopulmonary exercise, no further benefits beyond those obtained with a placebo were attained.

Indexed as

AthletesExercise TestOxygen ConsumptionAdultAthletic PerformanceBlood PressureDietary SupplementsDouble-Blind MethodFemaleHeart RateHumansMaleYoung Adultaerobic capacityanti-dopingcalf bloodcardiorespiratory fitnessSolcoserylVO2max

Identifiers

PMID39408298
PMCPMC11478799

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.