Evidence map›Paper›PMID 39408368›Full record

ArticleNutrients2024

Exploring Nutritional Status and Metabolic Imbalances in Children with FASD: A Cross-Sectional Study.

Katarzyna Anna Dylag, Wiktoria Wieczorek-Stawinska, Katarzyna Burkot, Lukasz Drzewiecki, Katarzyna Przybyszewska, Aleksandra Tokarz, Paulina Dumnicka

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Katarzyna Anna DylagDepartment of Pathophysiology, Jagiellonian University Medical College, 31-121 Krakow, Poland.ORCID 0000-0001-6886-0136
Wiktoria Wieczorek-StawinskaSt. Louis Children Hospital, 31-503 Krakow, Poland.
Katarzyna BurkotSt. Louis Children Hospital, 31-503 Krakow, Poland.
Lukasz DrzewieckiSt. Louis Children Hospital, 31-503 Krakow, Poland.
Katarzyna PrzybyszewskaSt. Louis Children Hospital, 31-503 Krakow, Poland.
Aleksandra TokarzSt. Louis Children Hospital, 31-503 Krakow, Poland.
Paulina DumnickaChair of Medical Biochemistry, Jagiellonian University Medical College, 31-034 Krakow, Poland.ORCID 0000-0003-3667-857X

Funding

National Agency for Prevention of Addictions 2358/13/11/2.1.2/H/DBMWM/2022.
6 · The paper itself

Abstract

BACKGROUND/

objectivesMalnutrition is a significant concern in paediatric populations, particularly among children with neurodevelopmental disorders such as foetal alcohol spectrum disorder (FASD). This study aimed to examine macronutrient and micronutrient imbalances and assess the nutritional status of a group of patients with FASD.

methodsThis study involved an analysis of the serum levels of key nutrients in a group of children diagnosed with FASD. Macronutrients and micronutrients were measured to identify any imbalances, including vitamin D, B12, E, A, albumin, and serum protein, among others.

resultsThe study found a high prevalence of vitamin D deficiency among the patients. Additionally, elevated serum concentrations of micronutrients such as vitamin B12, E, and A were observed in 8%, 7%, and 19% of patients, respectively. Macronutrient imbalances were noted, including high levels of albumin and serum protein, indicating a possible metabolic disturbance. Unexpectedly, high rates of hypercholesterolemia were observed, raising concerns about an increased risk of metabolic syndrome in this population.

conclusionsThese findings suggest that the principal issue among patients with FASD is an altered metabolism rather than nutritional deficiencies. Potential causes of these abnormalities could include oxidative stress and changes in body composition. The results underline the need for further research to better understand the unique nutritional challenges in children with FASD and to guide the development of targeted therapeutic strategies.

Indexed as

Fetal Alcohol Spectrum DisordersNutritional StatusAdolescentChildChild, PreschoolCross-Sectional StudiesFemaleHumansHypercholesterolemiaMaleMalnutritionMicronutrientsNutrientsPrevalenceVitamin D DeficiencyMicronutrientsNutrientsFASDfoetal alcohol spectrum disordermacronutrientmalnutritionmicronutrientnutrimetabolomicsPAEpaediatricprenatal alcohol exposure

Identifiers

PMID39408368
PMCPMC11478469

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.