Evidence map›Paper›PMID 39408369›Full record

ArticleNutrients2024

Genetic and Anthropometric Interplay: How Waist-to-Hip Ratio Modulates LDL-c Levels in Mexican Population.

César Hernández-Guerrero, Erika Arenas, Jaime García-Mena, Edgar J Mendivil, Omar Ramos-Lopez, Graciela Teruel

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

César Hernández-GuerreroDepartamento de Salud, Universidad Iberoamericana Ciudad de México, Mexico City 01219, Mexico.
Erika ArenasDepartment of Sociology, University of California, Santa Barbara, CA 93106, USA.ORCID 0000-0002-9478-9449
Jaime García-MenaDepartamento de Genética y Biología Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Mexico City 07360, Mexico.ORCID 0000-0002-0595-3711
Edgar J MendivilDepartamento de Salud, Universidad Iberoamericana Ciudad de México, Mexico City 01219, Mexico.
Omar Ramos-LopezMedicine & Psychology Faculty, Autonomous University of Baja California, Tijuana 22390, Mexico.ORCID 0000-0002-2505-1555
Graciela TeruelDivisión de Estudios Sociales, Universidad Iberoamericana Ciudad de México, Mexico City 01219, Mexico.

Funding

Ibero American University 17a.-Convocatoria-DINVP
6 · The paper itself

Abstract

BACKGROUND/

objectivesGenetic factors contribute to the physiopathology of obesity and its comorbidities. This study aimed to investigate the association of the SNPs

methodsThe study included 396 Mexican mestizo individuals with obesity and 142 individuals with normal weight. Biochemical markers were evaluated from peripheral blood samples, and SNP genotyping was performed using PCR with TaqMan probes. A genetic risk score (GRS) was computed using an additive model.

resultsNo significant associations were found between the SNPs

conclusionsA significant interaction between genetics and WHR influences LDL-c in Mexicans, which may contribute to the prevention and clinical management of dyslipidemia and cardiovascular disease.

Indexed as

Cholesterol, LDLObesityPolymorphism, Single NucleotideWaist-Hip RatioAdiponectinAdultAlpha-Ketoglutarate-Dependent Dioxygenase FTOAnthropometryATP Binding Cassette Transporter 1FemaleGenetic Predisposition to DiseaseGenotypeHumansMaleMexicoMiddle AgedABCA1 protein, humanAdiponectinADIPOQ protein, humanAlpha-Ketoglutarate-Dependent Dioxygenase FTOATP Binding Cassette Transporter 1Cholesterol, LDLFTO protein, humanLEPR protein, humanReceptors, LeptinABCA1ADIPOQFTOgenetic risk scoreGRB14LEPRobesitySNP

Identifiers

PMID39408369
PMCPMC11478600

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.