Evidence map›Paper›PMID 39408563›Full record

ArticleInternational journal of molecular sciences2024

Association of the rs9896052 Polymorphism Upstream of

Caroline Moura Cardoso Bastos, Lucas Marcelo da Silva Machado, Daisy Crispim, Luís Henrique Canani, Kátia Gonçalves Dos Santos

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Caroline Moura Cardoso BastosLaboratory of Human Molecular Genetics, Lutheran University of Brazil (ULBRA), Av. Farroupilha 8001, Canoas 92425-900, RS, Brazil.
Lucas Marcelo da Silva MachadoLaboratory of Human Molecular Genetics, Lutheran University of Brazil (ULBRA), Av. Farroupilha 8001, Canoas 92425-900, RS, Brazil.
Daisy CrispimEndocrine Division, Clinical Hospital of Porto Alegre (HCPA), R. Ramiro Barcelos 2350, Porto Alegre 90035-903, RS, Brazil.ORCID 0000-0001-5095-9269
Luís Henrique CananiDepartment of Internal Medicine, Federal University of Rio Grande do Sul (UFRGS), R. Ramiro Barcelos 2400, Porto Alegre 90035-003, RS, Brazil.
Kátia Gonçalves Dos SantosLaboratory of Human Molecular Genetics, Lutheran University of Brazil (ULBRA), Av. Farroupilha 8001, Canoas 92425-900, RS, Brazil.ORCID 0000-0001-5231-2071

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Growth factor receptor-bound protein 2 (GRB2) is a negative regulator of insulin signaling and a positive regulator of angiogenesis. Its expression is increased in a mouse model of retinal neovascularization and in patients with type 2 diabetes mellitus (T2DM). This case-control study aimed to investigate the association between the rs9896052 polymorphism (A>C) upstream of

Indexed as

Diabetes Mellitus, Type 2Diabetic RetinopathyGRB2 Adaptor ProteinPolymorphism, Single NucleotideAgedBrazilCase-Control StudiesFemaleGene FrequencyGenetic Predisposition to DiseaseGenotypeHumansMaleMiddle AgedGRB2 Adaptor ProteinGRB2 protein, humandiabetic retinopathygenetic associationGRB2polymorphismrs9896052type 2 diabetes mellitus

Identifiers

PMID39408563
PMCPMC11477274

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.