Evidence map›Paper›PMID 39408884›Full record

ArticleInternational journal of molecular sciences2024

Genome-Wide Association Study on Body Conformation Traits in Xinjiang Brown Cattle.

Menghua Zhang, Yachun Wang, Qiuming Chen, Dan Wang, Xiaoxue Zhang, Xixia Huang, Lei Xu

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Candidate genes related to growth and milk production in three Anatolian goats revealed by GWAS.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
    Article
  4. Article
  5. Genome-wide SNP evidence for the genetic uniqueness of indigenous cattle population.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Genome-Wide Association Studies in Japanese Quails of the FInternational journal of molecular sciences · 2025
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Menghua ZhangCollege of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.
Yachun WangLaboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture of China, National Engineering Laboratory of Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.ORCID 0000-0003-3629-2802
Qiuming ChenCollege of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.
Dan WangCollege of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.
Xiaoxue ZhangCollege of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.
Xixia HuangCollege of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.
Lei XuCollege of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.

Funding

National Modern Agriculture Industrial System Project No. CARS-36The Xinjiang brown cattle joint breeding population improvement and promotion action plan No. 2023XJHN-16The Xinjiang Uygur Autonomous Region Science and technology Aid Xinjiang Project No. 2018E02052
6 · The paper itself

Abstract

Body conformation traits are linked to the health, longevity, reproductivity, and production performance of cattle. These traits are also crucial for herd selection and developing new breeds. This study utilized pedigree information and phenotypic (1185 records) and genomic (The resequencing of 496 Xinjiang Brown cattle generated approximately 74.9 billion reads.) data of Xinjiang Brown cattle to estimate the genetic parameters, perform factor analysis, and conduct a genome-wide association study (GWAS) for these traits. Our results indicated that most traits exhibit moderate to high heritability. The principal factors, which explained 59.12% of the total variance, effectively represented body frame, muscularity, rump, feet and legs, and mammary system traits. Their heritability estimates range from 0.17 to 0.73, with genetic correlations ranging from -0.53 to 0.33. The GWAS identified 102 significant SNPs associated with 12 body conformation traits. A few of the SNPs were located near previously reported genes and quantitative trait loci (QTLs), while others were novel. The key candidate genes such as

Indexed as

Genome-Wide Association StudyPhenotypePolymorphism, Single NucleotideQuantitative Trait LociAnimalsBreedingCattleFemaleMalePedigreeQuantitative Trait, Heritablebody conformation traitsgenome-wide association studyquantitative trait lociXinjiang Brown cattle

Identifiers

PMID39408884
PMCPMC11476655

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.