Evidence map›Paper›PMID 39408916›Full record

ArticleInternational journal of molecular sciences2024

Comparative Analysis of the Cutaneous Microbiome in Psoriasis Patients and Healthy Individuals-Insights into Microbial Dysbiosis: Final Results.

Diana Sabina Radaschin, Alina Viorica Iancu, Alexandra Mariana Ionescu, Gabriela Gurau, Elena Niculet, Florin Ciprian Bujoreanu, Cristina Beiu, Alin Laurentiu Tatu, Liliana Gabriela Popa

Abstract readComparative Study
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Co-Occurrence ofInternational journal of molecular sciences · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Updates on Psoriasis in Special Areas.Journal of clinical medicine · 2024
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Diana Sabina RadaschinDepartment of Dermatology, "Saint Parascheva" Infectious Disease Clinical Hospital, 800179 Galati, Romania.
Alina Viorica IancuDepartment of Morphological and Functional Sciences, Faculty of Medicine and Pharmacy, "Dunarea de Jos" University, 800008 Galati, Romania.ORCID 0000-0001-5901-0818
Alexandra Mariana IonescuFaculty of Sciences and Environment, "Dunarea de Jos" University, 800008 Galati, Romania.
Gabriela GurauDepartment of Morphological and Functional Sciences, Faculty of Medicine and Pharmacy, "Dunarea de Jos" University, 800008 Galati, Romania.
Elena NiculetDepartment of Morphological and Functional Sciences, Faculty of Medicine and Pharmacy, "Dunarea de Jos" University, 800008 Galati, Romania.
Florin Ciprian BujoreanuDepartment of Dermatology, "Saint Parascheva" Infectious Disease Clinical Hospital, 800179 Galati, Romania.
Cristina BeiuDermatology Department, Carol Davila University of Medicine and Pharmacy, 030167 Bucharest, Romania.ORCID 0000-0003-4632-576X
Alin Laurentiu TatuDepartment of Dermatology, "Saint Parascheva" Infectious Disease Clinical Hospital, 800179 Galati, Romania.ORCID 0000-0003-4290-7068
Liliana Gabriela PopaDermatology Department, Carol Davila University of Medicine and Pharmacy, 030167 Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psoriasis is one of the most frequent chronic inflammatory skin diseases and exerts a significant psychological impact, causing stigmatization, low self-esteem and depression. The pathogenesis of psoriasis is remarkably complex, involving genetic, immune and environmental factors, some of which are still incompletely explored. The cutaneous microbiome has become more and more important in the pathogenesis of inflammatory skin diseases such as acne, rosacea, atopic dermatitis and psoriasis. Dysbiosis of the skin microbiome could be linked to acute flare ups in psoriatic disease, as recent studies suggest. Given this hypothesis, we conducted a study in which we evaluated the cutaneous microbiome of psoriasis patients and healthy individuals. In our study, we collected multiple samples using swab sampling, adhesive tape and punch biopsies. Our results are similar to other studies in which the qualitative and quantitative changes found in the cutaneous microbiome of psoriasis patients are different than healthy individuals. Larger, standardized studies are needed in order to elucidate the microbiome changes in psoriasis patients, clarify their role in the pathogenesis of psoriasis, decipher the interactions between the commensal microorganisms of the same and different niches and between microbiomes and the host and identify new therapeutic strategies.

Indexed as

DysbiosisMicrobiotaPsoriasisSkinAdultCase-Control StudiesFemaleHumansMaleMiddle Ageddysbiosisinflammatory skin diseasespsoriasisskin microbiome

Identifiers

PMID39408916
PMCPMC11477231

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.