Evidence map›Paper›PMID 39409111›Full record

ArticleInternational journal of molecular sciences2024

Heterogeneous Transcriptional Landscapes in Human Sporadic Parathyroid Gland Tumors.

Chiara Verdelli, Silvia Carrara, Riccardo Maggiore, Paolo Dalino Ciaramella, Sabrina Corbetta

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chiara VerdelliLaboratory of Experimental Biochemistry and Molecular Biology, IRCCS Ospedale Galeazzi-Sant'Ambrogio, 20157 Milan, Italy.ORCID 0000-0002-6644-5163
Silvia CarraraDepartment of Medical Biotechnology and Translational Medicine, University of Milan, 20133 Milan, Italy.
Riccardo MaggioreEndocrine Surgery, IRCCS Ospedale San Raffaele, 20132 Milan, Italy.ORCID 0000-0002-2869-9859
Paolo Dalino CiaramellaEndocrine Unit, ASST Ospedale Niguarda, 20162 Milan, Italy.
Sabrina CorbettaBone Metabolism Diseases and Diabetes Unit, IRCCS Istituto Auxologico Italiano, 20145 Milan, Italy.ORCID 0000-0001-8140-3175

Funding

Italian Ministry of Health no identification numberUniversity of Milan Linea 2
6 · The paper itself

Abstract

The expression of several key molecules is altered in parathyroid tumors due to gene mutations, the loss of heterozygosity, and aberrant gene promoter methylation. A set of genes involved in parathyroid tumorigenesis has been investigated in sporadic parathyroid adenomas (PAds). Thirty-two fresh PAd tissue samples surgically removed from patients with primary hyperparathyroidism (PHPT) were collected and profiled for gene, microRNA, and lncRNA expression (n = 27). Based on a gene set including

Indexed as

Gene Expression Regulation, NeoplasticParathyroid NeoplasmsAdenomaAdultAgedCyclin D1FemaleGene Expression ProfilingHumansHyperparathyroidism, PrimaryMaleMiddle AgedProto-Oncogene ProteinsReceptors, CalcitriolReceptors, Calcium-SensingRNA, Long NoncodingCASR protein, humanCCND1 protein, humanCyclin D1MEN1 protein, humanProto-Oncogene ProteinsReceptors, CalcitriolReceptors, Calcium-SensingRNA, Long NoncodingVDR protein, humancalcium-sensing receptorCDC73lncRNAsMEN1microRNAsparathormoneparathyroid tumors

Identifiers

PMID39409111
PMCPMC11476768

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.