Evidence map›Paper›PMID 39409116›Full record

ReviewInternational journal of molecular sciences2024

Antimicrobial Peptides Derived from Bacteria: Classification, Sources, and Mechanism of Action against Multidrug-Resistant Bacteria.

Raynichka Mihaylova-Garnizova, Slavena Davidova, Yordan Hodzhev, Galina Satchanska

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Raynichka Mihaylova-GarnizovaDepartment of Natural Sciences, New Bulgarian University, Montevideo Blvd. 21, 1618 Sofia, Bulgaria.
Slavena DavidovaDepartment of Natural Sciences, New Bulgarian University, Montevideo Blvd. 21, 1618 Sofia, Bulgaria.
Yordan HodzhevDepartment of Natural Sciences, New Bulgarian University, Montevideo Blvd. 21, 1618 Sofia, Bulgaria.ORCID 0000-0002-7770-3316
Galina SatchanskaDepartment of Natural Sciences, New Bulgarian University, Montevideo Blvd. 21, 1618 Sofia, Bulgaria.

Funding

Central Fund for Strategic Development, New Bulgarian University Grant NBU-GFSR-27/2024
6 · The paper itself

Abstract

Antimicrobial peptides (AMPs) are short, usually cationic peptides with an amphiphilic structure, which allows them to easily bind and interact with the cellular membranes of viruses, bacteria, fungi, and other pathogens. Bacterial AMPs, or bacteriocins, can be produced from Gram-negative and Gram-positive bacteria via ribosomal synthesis to eliminate competing organisms. Bacterial AMPs are vital in addressing the increasing antibiotic resistance of various pathogens, potentially serving as an alternative to ineffective antibiotics. Bacteriocins have a narrow spectrum of action, making them highly specific antibacterial compounds that target particular bacterial pathogens. This review covers the two main groups of bacteriocins produced by Gram-negative and Gram-positive bacteria, their modes of action, classification, sources of positive effects they can play on the human body, and their limitations and future perspectives as an alternative to antibiotics.

Indexed as

Anti-Bacterial AgentsAntimicrobial PeptidesDrug Resistance, Multiple, BacterialAnimalsBacteriaBacteriocinsGram-Negative BacteriaGram-Positive BacteriaHumansAnti-Bacterial AgentsAntimicrobial PeptidesBacteriocinsantibacterial mechanismantibiotic resistancebacterial AMPsbacteriocinsmodes of action

Identifiers

PMID39409116
PMCPMC11476732

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.