A Splice Site Variant in

Shernae A Woolley, Bethany Hopkins, Mehar S Khatkar, Ian V Jerrett, Cali E Willet, Brendon A O'Rourke, Imke Tammen

Abstract read

In one paragraph

Article in Animals : an open access journal from MDPI, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shernae A WoolleySydney School of Veterinary Science, Faculty of Science, The University of Sydney, Sydney, NSW 2006, Australia.

Bethany HopkinsSydney School of Veterinary Science, Faculty of Science, The University of Sydney, Sydney, NSW 2006, Australia.

Mehar S KhatkarSydney School of Veterinary Science, Faculty of Science, The University of Sydney, Sydney, NSW 2006, Australia.ORCID 0000-0002-4554-1404

Ian V JerrettAgriculture Victoria, AgriBio Centre, Bundoora, VIC 3083, Australia.

Cali E WilletSydney Informatics Hub, Core Research Facilities, The University of Sydney, Sydney, NSW 2006, Australia.ORCID 0000-0001-8449-1502

Brendon A O'RourkeElizabeth Macarthur Agricultural Institute, NSW Department of Primary Industries and Regional Development, Menangle, NSW 2568, Australia.ORCID 0000-0001-6959-9398

Imke TammenSydney School of Veterinary Science, Faculty of Science, The University of Sydney, Sydney, NSW 2006, Australia.ORCID 0000-0002-5520-6597

Funding

Australian Government Research Training Program Scholarship S. WoolleyErnesto Angrilli and Denis Russell Donation - inherited disease reserach in livestockSydney School of Veterinary Science, The University of Sydney Research student supportUniversity of Sydney and NSW Department of Primary Industries Compact funding

6 · The paper itself

Abstract

Pulmonary hypoplasia with anasarca, or hydrops fetalis, is characterized by stillbirth, diffuse oedema, and generalized lymph node hypoplasia. The enlarged fetus frequently causes dystocia. The disease has been reported in cattle and sheep as an inherited condition with a recessive mode of inheritance. This is the first report of the disease in Persian/Persian-cross sheep in Australia. Affected fetuses were reported from three flocks, and a total of eleven affected, eleven obligate carrier, and 188 related Persian/Persian-cross animals were available for analysis, as well as unrelated control animals. SNP genotyping revealed a region of homozygosity in affected animals on ovine chromosome six, which contained the functional candidate gene

Indexed as

hydrops fetalisinherited diseaserecessivesheepwhole genome sequencing

Identifiers

PMID39409761

DOI10.3390/ani14192811

PMCPMC11475510

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.