Evidence map›Paper›PMID 39409870›Full record

ArticleCancers2024

Enhancing the Efficacy of Breast Cancer Immunotherapy Using a Smac-Armed Oncolytic Virus.

Sijia Tang, Kristin V Lyles, Yuzhen Wang, Daping Fan, Ming Luo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sijia TangInstitute of Biomedical Sciences, Georgia State University, Atlanta, GA 30302, USA.ORCID 0009-0007-1357-2218
Kristin V LylesDepartment of Chemistry, Georgia State University, Atlanta, GA 30302, USA.ORCID 0000-0003-0395-673X
Yuzhen WangDepartment of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, SC 20209, USA.
Daping FanDepartment of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, SC 20209, USA.
Ming LuoDepartment of Chemistry, Georgia State University, Atlanta, GA 30302, USA.ORCID 0000-0003-1766-3487

Funding

Emodin as a chemopreventive agent for breast cancer - admin suppR01CA218578 · NCI · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI FAN, DAPING, MURPHY, ELIZABETH ANGELA · 2018 to 2022
$1.9M
NCI NIH HHS R01 CA218578
6 · The paper itself

Abstract

It has been shown that the response rate of TNBC is dependent on the level of PD-L1 and the tumor microenvironment (TME). Approaches that alter the TME can improve the efficacy of ICIs.

Indexed as

armed oncolytic viruscombination therapyimmunotherapymetastasispulmonary deliverySmactriple negative breast cancertumor microenvironment

Identifiers

PMID39409870
PMCPMC11476252

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.