Evidence mapPaperPMID 39409980Full record

ReviewCancers2024

The Role of Maximal TURBT in Muscle-Invasive Bladder Cancer: Balancing Benefits in Bladder Preservation and Beyond.

Farshad Sheybaee Moghaddam, Sami Dwabe, Nataliya Mar, Leila Safdari, Navin Sabharwal, Hanan Goldberg, Michael Daneshvar, Arash Rezazadeh Kalebasty

Abstract readReview
In one paragraph

Review in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Farshad Sheybaee MoghaddamInstitute of Urology, University of Southern California, Los Angeles, CA 90089, USA.
Sami DwabeDepartment of Medicine, University of California Irvine, Orange, CA 92868, USA.
Nataliya MarDepartment of Medicine, University of California Irvine, Orange, CA 92868, USA.
Leila SafdariDepartment of Medicine, University of Southern California, Los Angeles, CA 90089, USA.
Navin SabharwalDepartment of Urology, University of Irvine, Orange, CA 92868, USA.
Hanan GoldbergDepartment of Urology, SUNY Upstate Medical University, Syracuse, NY 13210, USA.
Michael DaneshvarDepartment of Urology, University of Irvine, Orange, CA 92868, USA.
Arash Rezazadeh KalebastyDepartment of Medicine, University of California Irvine, Orange, CA 92868, USA.ORCID 0000-0002-3701-5084

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radical cystectomy with lymph node dissection and urinary diversion is the gold-standard treatment for non-metastatic muscle-invasive bladder cancer (MIBC). However, in patients who refuse cystectomy, or in whom cystectomy carries a high risk, bladder-preserving therapies remain potential options. Bladder preservation therapies can include maximal debulking transurethral resection of bladder tumor (TURBT), concurrent chemoradiation therapy, followed by cystoscopy to assess response. At this time, maximal TURBT is recommended for patients prior to the initiation of chemoradiation therapy or in patients with residual bladder tumors after the completion of chemoradiation therapy. That being said, TURBT carries significant risks such as bladder perforation, bleeding, and infection, ultimately risking delayed systemic treatment. Hence, understanding its role within trimodal therapy is crucial to avoid undue suffering in patients. Herein, we review the current literature on the impact of debulking TURBT in non-metastatic MIBC.

Indexed as

bladder preservationbladder-sparingmuscle-invasive bladder cancerTrimodality treatmentTURBT

Identifiers

PMID39409980
PMCPMC11475991

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.