Evidence map›Paper›PMID 39410855›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2024

Association of MIND diet with cognitive decline among Black and White older adults.

Puja Agarwal, Lisa L Barnes, Klodian Dhana, Xiaoran Liu, Yanyu Zhang, Todd Beck, Marilyn C Cornelis, Christy Tangney, Kumar B Rajan

Abstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. MIND diet, cerebrovascular health, and cognition among community-dwelling older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
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  12. Validation of a MIND diet screener in older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
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  20. Association of MIND diet with cognitive decline among Black and White older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Puja AgarwalRush Alzheimer's Disease Center, Department of Internal Medicine, Department of Clinical Nutrition, Rush University Medical Center, Chicago, Illinois, USA.ORCID 0000-0002-0274-6653
Lisa L BarnesRush Alzheimer's Disease Center, Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA.
Klodian DhanaRush Institute of Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, USA.
Xiaoran LiuRush Institute of Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, USA.
Yanyu ZhangRush Institute of Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, USA.
Todd BeckRush Institute of Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, USA.
Marilyn C CornelisDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Christy TangneyDepartment of Family and Preventive Medicine, Department of Clinical Nutrition, Rush University Medical Center, Chicago, Illinois, USA.
Kumar B RajanRush Institute of Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, USA.

Funding

Impact of Neuroinflammation on AD Occurrence: A Bi-Generational Population StudyR01AG073627 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI NEELUM T. AGGARWAL, DENIS A EVANS · 2021 to 2026
$14.0M
Preserving Cognitive Resilience: A Biracial Parent-Offspring Study (18-4674) - Feasibility StudyR01AG058679 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI EVANS, DENIS A, RAJAN, KUMAR B. · 2019 to 2024
$13.8M
A Population-Based Latinx Community Study of Alzheimer’s DiseaseUH2AG083289 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI KRUEGER, KRISTIN R, RAJAN, KUMAR B. · 2023 to 2024
$1.1M
Alzheimer's Association Research AARG-21-852512NIA NIH HHS R01 AG058679NIA NIH HHS R01 AG073627NIA NIH HHS UH2 AG083289NIH HHS R01AG058679NIH HHS R01AG073627NIH HHS UH2AG083289
6 · The paper itself

Abstract

introductionWe examined the Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) diet's association with cognitive decline by race among older adults in the Chicago Health and Aging Project.

methodsFive thousand two hundred fifty-nine participants (73.5 [± 6.0] years, 62% Black participants, 62% female) completed a food frequency questionnaire, and two or more cognitive assessments over 7.8 ± 4.6 years.

resultsOverall, higher MIND diet was associated with slower cognitive decline (p for trend = 0.0025). The MIND score (range:0-15) was different between Black and White older adults(6.97 vs. 7.12, p = 0.010). Compared to the lowest tertile, among White participants, the two highest tertiles (MIND score -7: β = 0.0121 [95% confidence interval [CI]: 0.0006, 0.0237]; MIND score -8.5: β = 0.0146 [95% CI: 0.0003, 0.0260]) and among Black participants, only the highest tertile (MIND score -8.5: β = 0.0088 [95% CI: 0.0003, 0.0172]) had association with cognitive decline. Vascular and lifestyle factors attenuated the association only for Black older adults. DISCUSSION: The MIND diet was associated with slower cognitive decline in Black and White older adults, but this may vary with other lifestyle and vascular factors. Further research is warranted on race-specific cultural diets considering other risk factors for cognitive decline. HIGHLIGHTS: The intake of Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) diet components varies by race. The MIND diet may slow cognitive decline in both Black and White older adults. This association may vary with other lifestyle and vascular risk factors.

Indexed as

Black or African AmericanCognitive DysfunctionDietary Approaches To Stop HypertensionDiet, MediterraneanWhiteAgedChicagoFemaleHumansMaleagingAlzheimer's diseasecognitionhealthy dietary patternlongitudinalMediterranean–Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay dietrace differences

Identifiers

PMID39410855
PMCPMC11667540

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.