Evidence map›Paper›PMID 39412680›Full record

ArticleOrganic & biomolecular chemistry2025

Recognition of mixed-sequence double-stranded DNA regions using chimeric Invader/LNA probes.

Michaela E Everly, Raymond G Emehiser, Patrick J Hrdlicka

Abstract read
In one paragraph

Article in Organic & biomolecular chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michaela E EverlyDepartment of Chemistry, University of Idaho, Moscow, Idaho 83844-2343, USA. hrdlicka@uidaho.edu.
Raymond G EmehiserDepartment of Chemistry, University of Idaho, Moscow, Idaho 83844-2343, USA. hrdlicka@uidaho.edu.
Patrick J HrdlickaDepartment of Chemistry, University of Idaho, Moscow, Idaho 83844-2343, USA. hrdlicka@uidaho.edu.ORCID 0000-0002-8113-0450

Funding

Women's health: interplay of maternal diet and key demographics on neurological health in the rural frontier and remote WestP20GM103408 · NIGMS · UNIVERSITY OF IDAHO · PI Scott A Minnich · 2012 to 2026
$59.8M
NIGMS NIH HHS P20 GM103408
6 · The paper itself

Abstract

Development of robust oligonucleotide-based probe technologies, capable of recognizing specific regions of double-stranded DNA (dsDNA) targets, continues to attract considerable attention due to the promise of tools for modulation of gene expression, diagnostic agents, and new modalities against genetic diseases. Our laboratory pursues the development of various strand-invading probes. These include Invader probes,

Indexed as

DNAOligonucleotide ProbesOligonucleotidesBase SequenceDNAlocked nucleic acidOligonucleotide ProbesOligonucleotides

Identifiers

PMID39412680
PMCPMC11482323

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.