Evidence map›Paper›PMID 39416625›Full record

ArticlePakistan journal of medical sciences2024

Efficacy of butylphthalide in the treatment of patients with stroke attributed to intracranial arterial stenosis.

Xudong Lu, Shuxia Qian, Yanping Wang, Xiaoling Zhang, Yuhua Jin, Bo Yu

Abstract read
In one paragraph

Article in Pakistan journal of medical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xudong LuXudong Lu, Department of Neurology, Jiaxing Second Hospital, Jiaxing, Zhejiang Province 314000, P.R. China.
Shuxia QianShuxia Qian, Department of Neurology, Jiaxing Second Hospital, Jiaxing, Zhejiang Province 314000, P.R. China.
Yanping WangYanping Wang, Department of Neurology, Jiaxing Second Hospital, Jiaxing, Zhejiang Province 314000, P.R. China.
Xiaoling ZhangXiaoling Zhang, Department of Neurology, Jiaxing Second Hospital, Jiaxing, Zhejiang Province 314000, P.R. China.
Yuhua JinYuhua Jin, Department of Neurology, Jiaxing Second Hospital, Jiaxing, Zhejiang Province 314000, P.R. China.
Bo YuBo Yu, Department of Neurology, Jiaxing Second Hospital, Jiaxing, Zhejiang Province 314000, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the clinical efficacy of butylphthalide in treating patients with stroke attributed to intracranial artery stenosis (ICAS). Methods: In this retrospective study, records of 163 patients with stroke attributed to ICAS admitted to Jiaxing Second Hospital from January 2021 to January 2023 were retrospectively analyzed. Patients were divided into two groups based on the treatment received: control group (patients received routine treatment, n=55) and observation group (patients treated with butylphthalide on a routine basis, n=58). Changes in levels of cerebrovascular reactivity (CVR), breath-holding index (BHI), pulsatility index (PI), and middle cerebral artery mean flow velocity (Vm) between the two groups before and after treatment were compared. In addition, cognitive function, neurological function, and living ability were compared between the two groups before and after treatment, as well as the overall clinical efficacy of the treatment. Results: The baseline data was comparable between the two groups ( Conclusions: Butylphthalide in addition to routine treatment can effectively improve cerebrovascular reserve function, promote neurological and cognitive dysfunction recovery, and enhance daily living ability of patients with stroke caused by ICAS.

Indexed as

ButylphthalideIntracranial artery stenosisStroke

Identifiers

PMID39416625
PMCPMC11476165

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.