Evidence mapPaperPMID 39416751Full record

ArticleBJUI compass2024

Targeted Prostate Health Checks, a novel system to identify men with prostate cancer-A pilot study.

Stephen Langley, Jeremy Goad, Stephanie Bell, Lee Foster, Catherine Hodges, Marc Laniado, Michele Pietrasik, Alison Rooke, Matthew Knight, Edward Bosonnet and 1 more

Erratum issuedAbstract read
In one paragraph

Article in BJUI compass, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Erratum.BJUI compass · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Stephen LangleyThe Stokes Centre for Urology Royal Surrey Hospital NHS Foundation Trust Guildford UK.ORCID https://orcid.org/0000-0003-1785-2421
Jeremy GoadMedefer Ltd London UK.
Stephanie BellSurrey and Sussex Cancer Alliance Guildford UK.
Lee FosterSurrey and Sussex Cancer Alliance Guildford UK.
Catherine HodgesSurrey Primary Care Lead Surrey & Sussex Cancer Alliance Guildford UK.
Marc LaniadoWexham Park Hospital Slough Berkshire UK.
Michele PietrasikThe Stokes Centre for Urology Royal Surrey Hospital NHS Foundation Trust Guildford UK.
Alison RookeThe Stokes Centre for Urology Royal Surrey Hospital NHS Foundation Trust Guildford UK.
Matthew KnightMedefer Ltd London UK.ORCID https://orcid.org/0000-0003-1761-0115
Edward BosonnetMedefer Ltd London UK.
Simon BottFrimley Park Hospital, Frimley Health NHS Foundation Trust Frimley UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The objective of this study is to report the pilot phase of the Targeted Prostate Health Check programme that aims to identify men in the Surrey and Sussex region who have prostate cancer and who failed to be detected during the Covid era. Subjects and methods: Men aged 50 to 70, or 45 to 70 if Black or with a family history of prostate cancer, were identified from participating general practitioner (GP) records. Short message service (SMS) texts invited men to visit www.talkprostate.co.uk for information on prostate cancer and give consent to prostate-specific antigen (PSA) checks coordinated by a third-party virtual healthcare provider. Elevated age-related PSA levels, or levels below age-related thresholds but at 3 ng/mL or more, triggered referral to a rapid access urology clinic. GPs were informed of the results. Results: From 1842 text messages inviting 1549 people, 544 men consented to a PSA check. From 500 phlebotomy appointments, 485 (30% of invited men) took the PSA test of whom 68 (14%) were referred with an elevated PSA. After clinical review with multiparametric magnetic resonance imaging (mp-MRI), 22 patients underwent transperineal biopsies, and prostate cancer was detected in 18 men of whom 17 (95%) had clinically significant cancer. Conclusion: Our Targeted Prostate Cancer Health Check system identifies men at risk without burdening primary care. Awareness on prostate cancer risk was raised in 1549 invited men, half of whom were further educated via the registration website. One third of invited men were checked in whom clinically significant prostate cancer was found in 3.5%.

Indexed as

health checkmultiparametric‐MRIprostate cancerprostate‐specific antigenPSAtransperineal biopsy

Identifiers

PMID39416751
PMCPMC11479803

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.