Evidence map›Paper›PMID 39416887›Full record

ArticleNAR genomics and bioinformatics2024

MoNETA: MultiOmics Network Embedding for SubType Analysis.

Giovanni Scala, Luigi Ferraro, Aurora Brandi, Yan Guo, Barbara Majello, Michele Ceccarelli

Abstract read
In one paragraph

Article in NAR genomics and bioinformatics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. MiDNE a tool for Multi-omics genes and drugs interactions discovery.Computational and structural biotechnology journal · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Giovanni ScalaDepartment of Biology, University of Naples 'Federico II', 80128 Naples, Italy.
Luigi FerraroSylvester Comprehensive Cancer Center, University of Miami, 33136, Miami, USA.
Aurora BrandiDepartment of Biology, University of Naples 'Federico II', 80128 Naples, Italy.
Yan GuoSylvester Comprehensive Cancer Center, University of Miami, 33136, Miami, USA.
Barbara MajelloDepartment of Biology, University of Naples 'Federico II', 80128 Naples, Italy.
Michele CeccarelliSylvester Comprehensive Cancer Center, University of Miami, 33136, Miami, USA.ORCID https://orcid.org/0000-0002-4702-6617

Funding

Tumor Biology Research ProgramP30CA240139 · NCI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Stephen D. Nimer · 2019 to 2026
$24.1M
NCI NIH HHS P30 CA240139
6 · The paper itself

Abstract

Cells are complex systems whose behavior emerges from a huge number of reactions taking place within and among different molecular districts. The availability of bulk and single-cell omics data fueled the creation of multi-omics systems biology models capturing the dynamics within and between omics layers. Powerful modeling strategies are needed to cope with the increased amount of data to be interrogated and the relative research questions. Here, we present MultiOmics Network Embedding for SubType Analysis (MoNETA) for fast and scalable identification of relevant multi-omics relationships between biological entities at the bulk and single-cells level. We apply MoNETA to show how glioma subtypes previously described naturally emerge with our approach. We also show how MoNETA can be used to identify cell types in five multi-omic single-cell datasets.

Identifiers

PMID39416887
PMCPMC11482636

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.