Evidence map›Paper›PMID 39417621›Full record

ArticleOpen biology2024

SLMAP3 is crucial for organogenesis through mechanisms involving primary cilia formation.

Ana Paula Dias, Taha Rehmani, Billi Dawn Applin, Maysoon Salih, Balwant Tuana

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ana Paula DiasDepartment of Cellular and Molecular Medicine, University of Ottawa, Ottawa K1H 8M5, Canada.
Taha RehmaniDepartment of Cellular and Molecular Medicine, University of Ottawa, Ottawa K1H 8M5, Canada.
Billi Dawn ApplinDepartment of Cellular and Molecular Medicine, University of Ottawa, Ottawa K1H 8M5, Canada.
Maysoon SalihDepartment of Cellular and Molecular Medicine, University of Ottawa, Ottawa K1H 8M5, Canada.
Balwant TuanaDepartment of Cellular and Molecular Medicine, University of Ottawa, Ottawa K1H 8M5, Canada.ORCID 0000-0003-0835-3081

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DIANE BODURKA · 1985 to 2026
$290.8M
Functional Proteomics by Reverse Phase Protein Array in CancerR50CA221675 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI LU, YILING · 2017 to 2021
$726k
Canadian Institute of Health Research 220996-151999NCI NIH HHS P30 CA016672NCI NIH HHS R50 CA221675
6 · The paper itself

Abstract

SLMAP3 is a constituent of the centrosome and is known to assemble with the striatin-interacting phosphatase and kinase (STRIPAK) complex, where it has been reported to repress Hippo signalling. The global knockout of SLMAP3 in mice results in embryonic/perinatal lethality and stunted growth without changes in the phosphorylation status of YAP. Diverse phenotypes present in the SLMAP3

Indexed as

Membrane ProteinsOrganogenesisAnimalsCell PolarityCiliaDishevelled ProteinsEmbryo, MammalianEmbryonic DevelopmentFibroblastsMiceMice, KnockoutProtein IsoformsSignal TransductionDishevelled ProteinsDvl3 protein, mouseMembrane ProteinsProtein IsoformsSlmap protein, mouseFGFR1OP2Hippo pathwayPCPprimary ciliaSLMAP3STRIPAK

Identifiers

PMID39417621
PMCPMC11484480

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.