Evidence map›Paper›PMID 39419976›Full record

ReviewTranslational psychiatry2024

Harnessing the sensing and stimulation function of deep brain-machine interfaces: a new dawn for overcoming substance use disorders.

Danyang Chen, Zhixian Zhao, Jian Shi, Shengjie Li, Xinran Xu, Zhuojin Wu, Yingxin Tang, Na Liu, Wenhong Zhou, Changmao Ni and 7 more

Abstract readReview
In one paragraph

Review in Translational psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Danyang ChenDepartment of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.ORCID 0009-0006-2124-6845
Zhixian ZhaoDepartment of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Jian ShiSchool of Mechanical Science and Engineering, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Shengjie LiDepartment of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Xinran XuDepartment of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Zhuojin WuDepartment of Neurosurgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Yingxin TangDepartment of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Na LiuDepartment of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Wenhong ZhouWuhan Global Sensor Technology Co., Ltd, Wuhan, Hubei, China.
Changmao NiWuhan Neuracom Technology Development Co., Ltd, Wuhan, Hubei, China.
Bo MaMicrosystems Technology Center, School of Mechanical Science and Engineering, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Junya WangMicrosystems Technology Center, School of Mechanical Science and Engineering, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Jun ZhangSchool of Electrical Engineering and Automation, Wuhan University, Wuhan, Hubei, China.
Li HuangWuhan Neuracom Technology Development Co., Ltd, Wuhan, Hubei, China.
Zheng YouMicrosystems Technology Center, School of Mechanical Science and Engineering, Huazhong University of Science and Technology, Wuhan, Hubei, China. youz@hust.edu.cn.
Ping ZhangDepartment of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. ppkitty0609@163.com.ORCID 0000-0003-0858-8884
Zhouping TangDepartment of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. ddjtzp@163.com.ORCID 0000-0002-4153-8590

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82071330National Natural Science Foundation of China (National Science Foundation of China) 92148206
6 · The paper itself

Abstract

Substance use disorders (SUDs) imposes profound physical, psychological, and socioeconomic burdens on individuals, families, communities, and society as a whole, but the available treatment options remain limited. Deep brain-machine interfaces (DBMIs) provide an innovative approach by facilitating efficient interactions between external devices and deep brain structures, thereby enabling the meticulous monitoring and precise modulation of neural activity in these regions. This pioneering paradigm holds significant promise for revolutionizing the treatment landscape of addictive disorders. In this review, we carefully examine the potential of closed-loop DBMIs for addressing SUDs, with a specific emphasis on three fundamental aspects: addictive behaviors-related biomarkers, neuromodulation techniques, and control policies. Although direct empirical evidence is still somewhat limited, rapid advancements in cutting-edge technologies such as electrophysiological and neurochemical recordings, deep brain stimulation, optogenetics, microfluidics, and control theory offer fertile ground for exploring the transformative potential of closed-loop DBMIs for ameliorating symptoms and enhancing the overall well-being of individuals struggling with SUDs.

Indexed as

Brain-Computer InterfacesDeep Brain StimulationSubstance-Related DisordersBehavior, AddictiveBrainHumans

Identifiers

PMID39419976
PMCPMC11487193

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.