Evidence map›Paper›PMID 39421264›Full record

ArticleAnalytical cellular pathology (Amsterdam)2024

Exosomal PDL1 Suppresses the Anticancer Activity of CD8

Qi Hu, Shuai Chen, Rilin Deng, Hongyu Deng, Mingjing Peng, Xiaohong Wang, Shun Deng, Jinfeng Wang, Biaoming Xu, Yan Xu and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical cellular pathology (Amsterdam), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Qi HuGraduate Collaborative Training Base of Hunan Cancer Hospital, Hengyang Medical School, University of South China, Hengyang 421001, Hunan, China.
Shuai ChenSchool of Integrated Chinese and Western Medicine, Hunan University of Chinese Medicine, Changsha 410208, Hunan, China.
Rilin DengHunan Normal University School of Medicine, Changsha 410013, Hunan, China.
Hongyu DengDepartment of Gastroduodenal and Pancreatic Surgery, Translational Medicine Joint Research Center of Liver Cancer, Laboratory of Digestive Oncology, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Clinical Research Center for Tumor of Pancreaticobiliary Duodenal Junction in Hunan Provincial, Central South University, Changsha 410013, Hunan, China.
Mingjing PengDepartment of Gastroduodenal and Pancreatic Surgery, Translational Medicine Joint Research Center of Liver Cancer, Laboratory of Digestive Oncology, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Clinical Research Center for Tumor of Pancreaticobiliary Duodenal Junction in Hunan Provincial, Central South University, Changsha 410013, Hunan, China.
Xiaohong WangKey Laboratory of Tropical Translational Medicine of Ministry of Education, Department of Pathogen Biology, School of Basic Medicine and Life Science, Department of Clinical Laboratory of the Second Affiliated Hospital, The University of Hong Kong Joint Laboratory of Tropical Infectious Diseases, The Second Affiliated Hospital of Hainan Medical University, Hainan Medical University, Haikou 571199, Hainan, China.
Shun DengDepartment of Gastroduodenal and Pancreatic Surgery, Translational Medicine Joint Research Center of Liver Cancer, Laboratory of Digestive Oncology, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Clinical Research Center for Tumor of Pancreaticobiliary Duodenal Junction in Hunan Provincial, Central South University, Changsha 410013, Hunan, China.
Jinfeng WangDepartment of Gastroduodenal and Pancreatic Surgery, Translational Medicine Joint Research Center of Liver Cancer, Laboratory of Digestive Oncology, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Clinical Research Center for Tumor of Pancreaticobiliary Duodenal Junction in Hunan Provincial, Central South University, Changsha 410013, Hunan, China.
Biaoming XuGraduate Collaborative Training Base of Hunan Cancer Hospital, Hengyang Medical School, University of South China, Hengyang 421001, Hunan, China.
Yan XuHunan Normal University School of Medicine, Changsha 410013, Hunan, China.
Haizhen ZhuKey Laboratory of Tropical Translational Medicine of Ministry of Education, Department of Pathogen Biology, School of Basic Medicine and Life Science, Department of Clinical Laboratory of the Second Affiliated Hospital, The University of Hong Kong Joint Laboratory of Tropical Infectious Diseases, The Second Affiliated Hospital of Hainan Medical University, Hainan Medical University, Haikou 571199, Hainan, China.
Jinhai ZhengSchool of Biomedical Sciences, Hunan University, Changsha 410082, Hunan, China.
Man XiaDepartment of Gynecological Oncology, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School Medicine, Central South University, Changsha 410013, Hunan, China.ORCID https://orcid.org/0009-0002-6251-7470
Chaohui ZuoGraduate Collaborative Training Base of Hunan Cancer Hospital, Hengyang Medical School, University of South China, Hengyang 421001, Hunan, China.ORCID https://orcid.org/0000-0002-0835-7464

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor microenvironment (TME) is essential for the development and progression of hepatocellular carcinoma (HCC). Exosomes participate in constructing TME by passing biological information, but the regulatory effect of PDL1 in exosomes on anticancer activity of CD8

Indexed as

B7-H1 AntigenCarcinoma, HepatocellularCD8-Positive T-LymphocytesCell ProliferationExosomesLiver NeoplasmsAnimalsCell Line, TumorFemaleHumansMaleMiceMice, Inbred C57BLMiddle AgedTumor MicroenvironmentB7-H1 AntigenCD274 protein, human

Identifiers

PMID39421264
PMCPMC11483647

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.