Evidence map›Paper›PMID 39421749›Full record

ReviewFrontiers in immunology2024

Towards personalized vaccines.

Davide Montin, Veronica Santilli, Alessandra Beni, Giorgio Costagliola, Baldassarre Martire, Maria Felicia Mastrototaro, Giorgio Ottaviano, Caterina Rizzo, Mayla Sgrulletti, Michele Miraglia Del Giudice and 1 more

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  6. Large language models for bioinformatics.Quantitative biology (Beijing, China) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Davide MontinDivision of Pediatric Immunology and Rheumatology, "Regina Margherita" Children Hospital, Turin, Italy.
Veronica SantilliResearch Unit of Clinical Immunology and Vaccinology, Academic Department of Pediatrics (DPUO), IRCCS Bambino Gesù Children's Hospital, Rome, Italy.
Alessandra BeniDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Giorgio CostagliolaSection of Pediatric Hematology and Oncology, Azienda Ospedaliero Universitaria Pisana, Pisa, Italy.
Baldassarre MartireUnità Operativa Complessa (UOC) of Pediatrics and Neonatology, "Monsignor A.R. Dimiccoli" Hospital, Barletta, Italy.
Maria Felicia MastrototaroUnità Operativa Complessa (UOC) of Pediatrics and Neonatology, "Monsignor A.R. Dimiccoli" Hospital, Barletta, Italy.
Giorgio OttavianoDepartment of Pediatrics, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy.
Caterina RizzoDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Mayla SgrullettiPediatric Immunopathology and Allergology Unit, Policlinico Tor Vergata, University of Rome Tor Vergata, Rome, Italy.
Michele Miraglia Del GiudiceDepartment of Woman, Child and of General and Specialized Surgery, University of Campania "Luigi Vanvitelli", Naples, Italy.
Viviana MoschesePediatric Immunopathology and Allergology Unit, Policlinico Tor Vergata, University of Rome Tor Vergata, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emergence of vaccinomics and system vaccinology represents a transformative shift in immunization strategies, advocating for personalized vaccines tailored to individual genetic and immunological profiles. Integrating insights from genomics, transcriptomics, proteomics, and immunology, personalized vaccines offer the promise of enhanced efficacy and safety, revolutionizing the field of vaccinology. However, the development of personalized vaccines presents multifaceted challenges, including technical, ethical, economic, and regulatory considerations. Addressing these challenges is essential to ensure equitable access and safety of personalized vaccination strategies. Despite these hurdles, the potential of personalized vaccines to optimize responses and mitigate disease burden underscores the significance of ongoing research and collaboration in advancing precision medicine in immunization.

Indexed as

Precision MedicineVaccinesAnimalsGenomicsHumansVaccinationVaccine DevelopmentVaccinologyVaccinesgenomicsprecision medicineproteomicssystem vaccinologytranscriptomicsvaccinesvaccinomics and personalized vaccines

Identifiers

PMID39421749
PMCPMC11484009

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.