Evidence map›Paper›PMID 39422067›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

Acoustography by Beam Engineering and Acoustic Control Node: BEACON.

Wenjun Yu, Haodong Zhu, Neil Upreti, Brandon Lu, Xianchen Xu, Luke P Lee, Tony Jun Huang

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Acoustography by Beam Engineering and Acoustic Control Node: BEACON.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wenjun YuDepartment of Mechanical Engineering and Material Science, Duke University, Durham, NC, 27708, USA.
Haodong ZhuDepartment of Mechanical Engineering and Material Science, Duke University, Durham, NC, 27708, USA.
Neil UpretiDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Brandon LuDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Xianchen XuDepartment of Mechanical Engineering and Material Science, Duke University, Durham, NC, 27708, USA.
Luke P LeeHarvard Medical School, Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard University, Boston, MA, 02115, USA.ORCID https://orcid.org/0000-0002-1436-4054
Tony Jun HuangDepartment of Mechanical Engineering and Material Science, Duke University, Durham, NC, 27708, USA.ORCID https://orcid.org/0000-0003-1205-3313

Funding

Enabling Efficient, Fast, Biocompatible Exosome Separation via AcoustofluidicsR01GM132603 · NIGMS · DUKE UNIVERSITY · PI HUANG, TONY JUN · 2019 to 2022
$1.7M
National Science Foundation CMMI-2104295NIGMS NIH HHS R01 GM132603NIH HHS R01GM132603
6 · The paper itself

Abstract

Acoustic manipulation has emerged as a valuable tool for precision controls and dynamic programming of cells and particles. However, conventional acoustic manipulation approaches lack the finesse necessary to form intricate, configurable, continuous, and 3D patterning of particles. Here, this study reports acoustography by Beam Engineering and Acoustic Control Node (BEACON), which delivers intricate, configurable patterns by guiding particles along custom paths with independent phase modulation. Leveraging analytical methods of orbital angular momentum beam via iterative Wirtinger hologram algorithm, this study accomplish acoustography by facilitating orbital angular momentum traps, enabling continuous 2D and 3D acoustic manipulation of microparticles in any desired geometry, with phase modulation independent of intensity. Utilizing on-chip acoustography, the BEACON platform markedly increases the space-bandwidth product to 31 000 while attaining an enhanced resolution with a pixel size of ≈25 µm, surpassing the typical resolution of over 200 µm in previous holographic particle manipulation methods. The capabilities of BEACON are demonstrated in creating intricate triple helical tracing structures using microdroplets (20 µm in diameter) and those carrying DNA to validate the effectiveness of the acoustography and phase control methods. This study offers new particle manipulation opportunities, paving the way for next-generation biomedical systems and the future of contact-free precision manufacturing.

Indexed as

acoustic manipulationacoustofluidicsorbital angular momentum (OAM) beam

Identifiers

PMID39422067
PMCPMC11633508

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.