Evidence map›Paper›PMID 39422147›Full record

ArticleThe British journal of nutrition2024

Serum concentrations of lipids, ketones and acylcarnitines during the postprandial and fasting state: the Postprandial Metabolism (PoMet) study in healthy young adults.

Åslaug Matre Anfinsen, Vilde Haugen Myklebust, Christina Osland Johannesen, Jacob Juel Christensen, Johnny Laupsa-Borge, Jutta Dierkes, Ottar Nygård, Adrian McCann, Hanne Rosendahl-Riise, Vegard Lysne

Abstract read
In one paragraph

Article in The British journal of nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Åslaug Matre AnfinsenMohn Nutrition Research Laboratory, Centre for Nutrition, Department of Clinical Science, University of Bergen, Bergen, Norway.ORCID 0000-0003-3640-7673
Vilde Haugen MyklebustMohn Nutrition Research Laboratory, Centre for Nutrition, Department of Clinical Science, University of Bergen, Bergen, Norway.
Christina Osland JohannesenMohn Nutrition Research Laboratory, Centre for Nutrition, Department of Clinical Science, University of Bergen, Bergen, Norway.
Jacob Juel ChristensenDepartment of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.ORCID 0000-0001-8008-0650
Johnny Laupsa-BorgeMohn Nutrition Research Laboratory, Centre for Nutrition, Department of Clinical Science, University of Bergen, Bergen, Norway.
Jutta DierkesMohn Nutrition Research Laboratory, Centre for Nutrition, Department of Clinical Medicine, University of Bergen, Bergen, Norway.
Ottar NygårdMohn Nutrition Research Laboratory, Centre for Nutrition, Department of Clinical Science, University of Bergen, Bergen, Norway.
Adrian McCannBevital AS, Bergen, Norway.
Hanne Rosendahl-RiiseMohn Nutrition Research Laboratory, Centre for Nutrition, Department of Clinical Medicine, University of Bergen, Bergen, Norway.ORCID 0000-0002-1497-416X
Vegard LysneMohn Nutrition Research Laboratory, Centre for Nutrition, Department of Clinical Science, University of Bergen, Bergen, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To improve the interpretation and utilisation of blood lipids, ketones and acylcarnitine concentrations as biomarkers in clinical assessments, more information is needed on their dynamic alterations in response to dietary intake and fasting. The aim of this intervention study was to characterise the changes in serum lipid, ketone and acylcarnitine concentrations 24 h after a standardised breakfast meal. Thirty-four healthy subjects (eighteen males and sixteen females) aged 20-30 years were served a breakfast meal (∼500 kcal, 36 E% fat, 46 E% carbohydrates, 16 E% protein, 2E% fibre), after which they consumed only water for 24 h. Blood samples were drawn before and at thirteen standardised timepoints after the meal. Metabolite concentrations were plotted as a function of time since the completion of the breakfast meal. Results demonstrated that concentrations of HDL-cholesterol and LDL-cholesterol decreased until ∼2 h (-4 % for both), while TAG concentrations peaked at 3 h (+27 %). Acetoacetate and

Indexed as

CarnitineFastingKetonesPostprandial PeriodTriglycerides3-Hydroxybutyric AcidAcetoacetatesAdultBiomarkersBreakfastCholesterol, HDLCholesterol, LDLFemaleHumansLipidsMale3-Hydroxybutyric AcidAcetoacetatesacetoacetic acidacylcarnitineBiomarkersCarnitineCholesterol, HDLCholesterol, LDLKetonesLipidsTriglyceridesAcylcarnitinesBiomarkersCarnitineEpidemiologyFastingMetabolismMetabolitesMetabolomicsPostprandial response

Identifiers

PMID39422147
PMCPMC11576092

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.