Evidence map›Paper›PMID 39422192›Full record

ArticleEuropean journal of cardiovascular nursing2025

Psychological factors and blood pressure responses to acute stress in women with takotsubo syndrome: an exploratory study.

Sara Ouaddi, Natalie G Keirns, Sharon Y Lee, Shira Dunsiger, Emily Gathright, Matthew Burg, Christopher Breault, Janice Tripolone, Elena Salmoirago-Blotcher

Abstract read
In one paragraph

Article in European journal of cardiovascular nursing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Chronic adrenocortical activity and onset of Takotsubo syndrome.European journal of cardiovascular nursing · 2026
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sara OuaddiBrown University Health Cardiovascular Institute, The Miriam Hospital, 180 Corliss St, Providence, RI 02904, USA.
Natalie G KeirnsBrown University Health Cardiovascular Institute, The Miriam Hospital, 180 Corliss St, Providence, RI 02904, USA.ORCID 0000-0002-1455-7964
Sharon Y LeeCenter for Behavioral and Preventive Medicine, The Miriam Hospital, Providence, RI, USA.
Shira DunsigerDepartment of Behavioral and Social Sciences, School of Public Health, Brown University, Providence, RI, USA.
Emily GathrightCenter for Behavioral and Preventive Medicine, The Miriam Hospital, Providence, RI, USA.
Matthew BurgSection of Cardiovascular Medicine, Yale School of Medicine, New Haven, CT, USA.
Christopher BreaultCenter for Behavioral and Preventive Medicine, The Miriam Hospital, Providence, RI, USA.
Janice TripoloneBrown University Health Cardiovascular Institute, The Miriam Hospital, 180 Corliss St, Providence, RI 02904, USA.
Elena Salmoirago-BlotcherBrown University Health Cardiovascular Institute, The Miriam Hospital, 180 Corliss St, Providence, RI 02904, USA.

Funding

Stress and resilience in women with Takotsubo syndrome: Admin SupplementR01HL149672 · NHLBI · MIRIAM HOSPITAL · PI SALMOIRAGO-BLOTCHER, ELENA · 2020 to 2024
$2.9M
NHLBI NIH HHS R01 HL149672NHLBI NIH HHS R01HL149672NIH HHS
6 · The paper itself

Abstract

aimsThis secondary analysis aimed to (i) describe psychological resources and distress in women with takotsubo syndrome (TS) and (ii) explore whether such factors affect blood pressure (BP) responses to acute mental stress. METHODS AND

resultsParticipants were 47 women consecutively enrolled in an ongoing study examining the prognostic significance of stress reactivity in TS. Psychological resources (resilience and adaptive coping) and distress [depression, anxiety, post-traumatic stress disorder (PTSD), and perceived stress] were self-reported using validated questionnaires <12 weeks after TS. Using a standardized protocol, systolic BP (SBP) and diastolic BP (DBP) (mmHg) were measured every 5 min during baseline (10 min), mental stress (10 min), and recovery (20 min). Associations of psychological resources and distress (high vs. low composite scores), respectively, with BP during mental stress and recovery (change from baseline), were examined using one-way analyses of covariance (covariates: age and anti-hypertensive medications). Given the study's exploratory nature, results are shown as effect sizes. On average, women (Mage = 64.3 years) had high perceived stress, anxiety, and PTSD symptoms and low resilience. Women with high (vs. low) psychological distress displayed less complete SBP (d = 0.57) and DBP (d = 0.33) recovery to baseline. Women with low (vs. high) psychological resources demonstrated lower SBP responses during mental stress (d = -0.26) alongside a more complete SBP recovery (d = 0.30).

conclusionFemale survivors of TS with high psychological distress exhibited impaired BP recovery following acute mental stress. While the prognostic significance of impaired BP recovery from mental stress remains to be determined in longitudinal studies, this finding could help identify TS survivors at risk for recurrence.

Indexed as

Blood PressureStress, PsychologicalTakotsubo CardiomyopathyAdaptation, PsychologicalAgedAnxietyFemaleHumansMiddle AgedResilience, PsychologicalStress Disorders, Post-TraumaticSurveys and QuestionnairesBlood pressurePositive psychological resourcesPsychological distressStressTakotsubo syndromeWomen

Identifiers

PMID39422192
PMCPMC11986365

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.