ArticleJournal of racial and ethnic health disparities2025
Obesity and Left Ventricular Function in American Indian Adolescents: Strong Heart Family Study.
Article in Journal of racial and ethnic health disparities, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Environmental Exposures and Atherosclerotic Risk Factors in Vulnerable Youth: The Example of American Indian/Alaska Native Populations.Current atherosclerosis reports · 2026Review
- Cardiac Catheterization in American Indian/Alaska Native Populations: Empowering Communities, Providers, and Systems Toward Equity.Journal of the Society for Cardiovascular Angiography & Interventions · 2026Review
- Improving American Indian Adolescent and Young Adult Cardiovascular Health: The Importance of the Strong Heart Family Study.Journal of the American Heart Association · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesObesity is a known risk factor for developing cardiovascular disease (CVD). American Indian (AI) children have the highest obesity rates of all racial/ethnic groups in the United States (US). However, cardiometabolic health among AI adolescents is understudied. The purpose of this study was to describe the cardiometabolic characteristics of AI adolescents enrolled in the Strong Heart Family Study (SHFS), a longitudinal study of CVD from 12 AI communities, and associations with the development of abnormal left ventricular mass index (LVMI) and ejection fraction (EF). STUDY
designThis study included AI youth ages 14-22 years. Primary outcome variables were depressed EF (< 55%) and abnormal LVMI at 6-year follow-up. The primary predictor variable was BMI. Covariates included sex, cholesterol levels, blood pressure, and hemoglobin A1c. Wilcoxon signed-rank test for matched pairs evaluated cardiometabolic trends over time. Stratified univariate logistic regression by obese/nonobese categories evaluated associations with depressed EF and abnormal LVMI.
resultsThere were 384 subjects, 58% of whom were overweight (n = 87) or obese (n = 122) at baseline. Among overweight/obese subjects, cholesterol and triglyceride levels were elevated. At 6-year follow-up, BMI increased while EF decreased among overweight/obese males, with 3.6 times the odds of having depressed EF (95% CI 1.22-10.98, p = 0.021) compared to normal-weight males. There were no significant cardiometabolic associations with LVMI.
conclusionsThis is one of the largest longitudinal evaluations of CVD in AI adolescents. Concerning trends in BMI and depressed EF among AI males suggest the importance of culturally competent interventions to promote healthy weight and reduce cardiometabolic risk.
Indexed as
Identifiers
39422831What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.