Evidence map›Paper›PMID 39423035›Full record

ReviewAmerican journal of physiology. Heart and circulatory physiology2024

The role of T cells in vascular aging, hypertension, and atherosclerosis.

Theodore M DeConne, David J Buckley, Daniel W Trott, Christopher R Martens

Abstract readReview
In one paragraph

Review in American journal of physiology. Heart and circulatory physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Type 2 Diabetes From the Perspective of Telomere Biology.Endocrinology, diabetes & metabolism · 2026
    Review
  6. Article
  7. Observational
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Theodore M DeConneDepartment of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States.ORCID 0000-0002-9704-6499
David J BuckleyDepartment of Kinesiology, University of Texas at Arlington, Arlington, Texas, United States.ORCID 0000-0002-0145-8764
Daniel W TrottDepartment of Kinesiology, University of Texas at Arlington, Arlington, Texas, United States.ORCID 0000-0003-4872-4422
Christopher R MartensDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware, United States.ORCID 0000-0003-0578-2948

Funding

Vascular Consequences of Duchenne Muscular DystrophyP20GM113125 · NIGMS · UNIVERSITY OF DELAWARE · PI FANCHER, IBRA · 2016 to 2025
$23.3M
NIGMS NIH HHS P20 GM113125
6 · The paper itself

Abstract

Vascular dysfunction has emerged as a significant risk factor for the development of cardio- and cerebrovascular diseases (CVDs), which are currently the leading cause of morbidity and mortality worldwide. T lymphocytes (T cells) have been shown to be important modulators of vascular function in primary aging and CVDs, likely by producing inflammatory cytokines and reactive oxygen species that influence vasoprotective molecules. This review summarizes the role of T cells on vascular function in aging, hypertension, and atherosclerosis in animals and humans, and discusses potential T-cell targeted therapeutics to prevent, delay, or reverse vascular dysfunction.

Indexed as

AgingAtherosclerosisHypertensionT-LymphocytesAnimalsBlood VesselsHumansinflammationoxidative stressT cellsvascular dysfunction

Identifiers

PMID39423035
PMCPMC12312734

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.