ArticleJournal of clinical monitoring and computing2025
Time to maximum pupil constriction is variable in neurocritical care patients.
Article in Journal of clinical monitoring and computing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- There Is Significant Within-Subject Variation in the Time from Light Stimulus to Maximum Pupil Constriction Among Healthy Controls.Journal of clinical medicine · 2024Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Quantitative pupillometry (QP) use has grown exponentially. Each QP scan captures images of the pupil before, during, and after light exposure to provide component measures of the pupillary light reflex (PLR). This study explores if the time to maximum constriction (tMC) is uniform among neuroscience intensive care unit (NSICU) patients. The study enrolled 50 NSICU patients with normal PLR values in a cross-sectional study and adhered to the standard of care for pupil assessments to collect data on tMC within (comparing left eye and right eye) and between patients. The mean tMC of 0.97 (0.17) s was normally distributed across all patients and ranged from 0.46 s to 1.35 s. The mean tMC was similar for the left pupil (0.98 [0.16]s) and right pupil (0.96 [0.18]s; P =.546). The within-subject mean difference (left versus right eye) tMC was 0.13 (0.12)s and ranged from 0.0 to 0.56 s. The between-subject mean tMC was 0.97 (0.17) s and ranged from 0.46 s to 1.35 s. The tMC does not occur at a fixed point in time. Clinical applications that seek to characterize pupil health should account for varied tMC and explore relationships to discrete outcomes to determine the clinical usefulness of tMC.
Indexed as
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39424741What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.