ArticleActa paediatrica (Oslo, Norway : 1992)2025
Reference values for cerebral and peripheral tissue oximetry in children: A clinical TD-NIRS study.
Article in Acta paediatrica (Oslo, Norway : 1992), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Bridging the gap: Translating fetal, infant, and toddler neuroimaging insights into clinical practice.Developmental cognitive neuroscience · 2026Review
- Reliability of diffuse optical spectroscopies for evaluation of cerebral hemometabolic stress in children with sickle cell anemia.Biomedical optics express · 2026Article
- Quantitative analysis of tissue oxygenation variability across anatomical landmarks in healthy individuals via near-infrared spectroscopy.Scientific reports · 2025Article
- Reference values for cerebral and peripheral tissue oximetry in children: A clinical TD-NIRS study.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Evaluation of monitoring critical ill children with traumatic brain injury.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2025Article
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Authors and funding
9 authors.
Funding
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Abstract
aimCurrent non-invasive near-infrared spectroscopy (NIRS) tissue oximetry suffers from suboptimal reproducibility over probe repositioning, hindering clinical threshold establishment. Time Domain-NIRS (TD-NIRS) offers higher precision but lacks sufficient paediatric data, preventing effective clinical application. We aimed to establish reference ranges for cerebral and mid-upper arm (MUA) tissue haemodynamics in paediatric subjects using TD-NIRS and explore correlations with auxological variables.
methodsTD-NIRS measurements were conducted acquiring data from cerebral and MUA regions with the NIRSBOX tissue oximeter. Morphological and clinically relevant information were collected to explore potential correlations with TD-NIRS derived parameters.
resultsTD-NIRS assessment was applied in 350 children (8.4 ± 5.0 years). Precision of TD-NIRS was demonstrated with standard deviations of 0.9% (StO
conclusionThis study reports resting-state optical and haemodynamic values for a healthy paediatric population, providing a foundation for future investigations into clinically relevant deviations in these parameters. Furthermore, correlations with anthropometric and demographic values provide valuable insights for a deeper understanding of tissue haemodynamic evolution in childhood.
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