ReviewAlzheimer's & dementia : the journal of the Alzheimer's Association2024
Arterial spin labeling perfusion MRI in the Alzheimer's Disease Neuroimaging Initiative: Past, present, and future.
Review in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- Denoising of ASL Data Using Deep Learning Priors Generated From Distribution Remapping.Magnetic resonance in medicine · 2026Article
- Multiple-TE Based Blood-Brain-Barrier Water Exchange Time Measurement Using a TE-Resolved 3D TSE Stack-Of-Spirals Readout.Magnetic resonance in medicine · 2026Article
- Contributions of the Alzheimer's Disease Neuroimaging Initiative to advancing AD research: a targeted review of recent publications.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Screening for Alzheimer's disease in the community using an AI-driven screening platform: design of the PREDICTOM study.The journal of prevention of Alzheimer's disease · 2026Article
- Simultaneous multiple post-labelling delay ASL MRI and [European journal of nuclear medicine and molecular imaging · 2026Article
- The Biomarker Profile of Alzheimer's Disease for Disease-Modifying Treatment Eligibility: Questions and Debates.International journal of molecular sciences · 2025Review
- Multimodal neuroimaging unveils basal forebrain-limbic system circuit dysregulation in cognitive impairment with depression: a pathway to early diagnosis and intervention.The journal of prevention of Alzheimer's disease · 2025Article
- Hippocampal subfields in aging: Sex-specific trajectories in structure and hemodynamics.NeuroImage · 2025Article
- Development of a Predictive Model for the Progression of Subjective Cognitive Decline: A Longitudinal Study.Brain and behavior · 2025Article
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- Arterial spin labeling perfusion MRI in the Alzheimer's Disease Neuroimaging Initiative: Past, present, and future.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Review
- The clinical value of multimodal neuroimaging in monoclonal antibody therapy for Alzheimer's disease.Frontiers in neurologyReview
- Generative diffusion model enables quantification of calibration-free arterial spin labeling perfusion magnetic resonance imaging data in an Alzheimer's disease cohort.Alzheimer's & dementia (Amsterdam, Netherlands)Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
On the 20th anniversary of the Alzheimer's Disease Neuroimaging Initiative (ADNI), this paper provides a comprehensive overview of the role of arterial spin labeling (ASL) magnetic resonance imaging (MRI) in understanding perfusion changes in the aging brain and the relationship with Alzheimer's disease (AD) pathophysiology and its comorbid conditions. We summarize previously used acquisition protocols, available data, and the motivation for adopting a multi-post-labeling delay (PLD) acquisition scheme in the latest ADNI MRI protocol (ADNI 4). We also detail the process of setting up this scheme on different scanners, emphasizing the potential of ASL imaging in future AD research. HIGHLIGHTS: The Alzheimer's Disease Neuroimaging Initiative (ADNI) adopted multimodal arterial spin labeling magnetic resonance imaging (ASL MRI) to meet evolving biomarker requirements. The ADNI provides one of the largest multisite, multi-vendor ASL data collections. The ADNI 4 incorporates multi-post-labeling delay ASL techniques to jointly quantify cerebral blood flow and arterial transit time. ADNI 4 ASL MRI protocol is apt for detecting early Alzheimer's disease with cerebrovascular pathology.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.