Evidence map›Paper›PMID 39429198›Full record

ArticleHypertension (Dallas, Tex. : 1979)2024

8-Aminopurines: A Promising New Direction for Purine-Based Therapeutics.

Edwin K Jackson, Stevan P Tofovic, Yuanyuan Chen, Lori A Birder

Abstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Edwin K JacksonDepartment of Pharmacology and Chemical Biology (E.K.J., S.P.T., Y.C., L.A.B.), University of Pittsburgh School of Medicine, Pittsburgh, PA.ORCID 0000-0002-8101-6009
Stevan P TofovicDepartment of Pharmacology and Chemical Biology (E.K.J., S.P.T., Y.C., L.A.B.), University of Pittsburgh School of Medicine, Pittsburgh, PA.
Yuanyuan ChenDepartment of Pharmacology and Chemical Biology (E.K.J., S.P.T., Y.C., L.A.B.), University of Pittsburgh School of Medicine, Pittsburgh, PA.
Lori A BirderDepartment of Pharmacology and Chemical Biology (E.K.J., S.P.T., Y.C., L.A.B.), University of Pittsburgh School of Medicine, Pittsburgh, PA.

Funding

Single Nephron and MetabolomicsP30DK079307 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KLEYMAN, THOMAS R · 2008 to 2022
$13.4M
The Guanosine-Adenosine MechanismR01HL109002 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JACKSON, EDWIN KERRY · 2012 to 2023
$5.1M
PNPase inhibition as an effective treatment for chronic bladder painR01DK135076 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BIRDER, LORI A, JACKSON, EDWIN KERRY · 2022 to 2025
$3.9M
Bladder Mucosal Dysfunction During AgingR01AG056944 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI APODACA, GERARD L, BIRDER, LORI A · 2018 to 2022
$3.2M
Role of Purine Dysregulation in the Underactive BladderR56AG063753 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BIRDER, LORI A, JACKSON, EDWIN KERRY · 2019 to 2019
$691k
NHLBI NIH HHS R01 HL109002NIA NIH HHS R01 AG056944NIA NIH HHS R56 AG063753NIDDK NIH HHS P30 DK079307NIDDK NIH HHS R01 DK135076
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

guanosinehypertensioninosinepurine nucleoside phosphorylase

Identifiers

PMID39429198
PMCPMC11578759

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.