Evidence map›Paper›PMID 39430587›Full record

ArticleFrontiers in medicine2024

Psychological factors and biochemical indicators influencing sleep disturbance of patients with primary biliary cholangitis in China: a cross-sectional survey analysis.

Chenyang Zhao, Bo Zang, Qixuan Liu, Bingqian Liu, Yuan Yao, Hua Li, Yifei Yang, Bin Liu

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Article in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Chenyang ZhaoDepartment of Rheumatology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Bo ZangDepartment of Rheumatology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Qixuan LiuBoston University, Boston, MA, United States.
Bingqian LiuDepartment of Rheumatology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Yuan YaoDepartment of Rheumatology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Hua LiDepartment of Rheumatology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Yifei YangDepartment of Rheumatology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Bin LiuDepartment of Rheumatology, The Affiliated Hospital of Qingdao University, Qingdao, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The impact of primary biliary cholangitis (PBC) on sleep disturbance is relevant to treatment decision-making processes. Studies on sleep disturbance in Chinese patients with PBC are still lacking. Methods: We analyzed and compared the health-related quality of life (HRQoL) of 107 PBC patients by using the Pittsburgh Sleep Quality Index (PSQI) questionnaire, Generalized Anxiety Disorder Scale (GAD-7), Patient Health Questionnaire 9 (PHQ-9), Short Form (36) Health Survey Questionnaire (SF-36), Fatigue Visual Analog Scale (F-VAS). Patients' biochemical markers were also collected for correlation analysis with HRQoL. Receiver operating characteristic (ROC) curves and area under the curve (AUCs) were used to determine the diagnostic performance of PSQI, GAD-7, and biochemical markers for assessing the impaired liver function (Child-Pugh B-C) of PBC diagnosis. Results: Sixty-two (57.9%) PBC patients suffered from poor sleep quality (PSQI >5). The global PSQI score was positively correlated with GAD-7 ( Conclusion: The sleep disturbance was strongly correlated with the severity of anxiety, depression, and RBC count in PBC patients. Meanwhile, PBC patients with poor sleep had poor HRQoL and lower albumin levels. It is feasible to use the combination of PSQI, GAD-7, and RBC for initial screening of the impaired liver function in PBC. Besides routine blood biochemical and imaging indicators, evaluating mental health-related indicators in PBC patients is imperative.

Indexed as

generalized anxiety disorder scalepatient health questionnairePittsburgh sleep quality indexprimary biliary cholangitissleep disturbance

Identifiers

PMID39430587
PMCPMC11488817

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.