Evidence map›Paper›PMID 39435704›Full record

Trial reportJournal of the American Heart Association2024

Oxygen Delivery and Consumption in Patients Who Are Comatose After Out-of-Hospital Cardiac Arrest Are Affected by Blood Pressure Target.

Simon Schneekloth, Rasmus Paulin Beske, Jacob Eifer Møller, Laust E R Obling, Jesper Kjaergaard, Martin A S Meyer, Johannes Grand, Henrik Schmidt, Henrik Frederiksen Højgaard, Christian Hassager

Abstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Simon SchneeklothDepartment of Cardiology, The Heart Centre Copenhagen University Hospital Copenhagen Denmark.ORCID 0009-0000-2786-3736
Rasmus Paulin BeskeDepartment of Cardiology, The Heart Centre Copenhagen University Hospital Copenhagen Denmark.ORCID 0000-0002-5880-3733
Jacob Eifer MøllerDepartment of Cardiology, The Heart Centre Copenhagen University Hospital Copenhagen Denmark.ORCID 0000-0003-2873-5845
Laust E R OblingDepartment of Cardiology, The Heart Centre Copenhagen University Hospital Copenhagen Denmark.ORCID 0000-0003-2927-3670
Jesper KjaergaardDepartment of Cardiology, The Heart Centre Copenhagen University Hospital Copenhagen Denmark.ORCID 0000-0001-5244-0399
Martin A S MeyerDepartment of Cardiology, The Heart Centre Copenhagen University Hospital Copenhagen Denmark.
Johannes GrandDepartment of Cardiology, The Heart Centre Copenhagen University Hospital Copenhagen Denmark.ORCID 0000-0002-5511-4668
Henrik SchmidtDepartment of Clinical Research University of Southern Denmark Odense Denmark.ORCID 0000-0003-1080-3344
Henrik Frederiksen HøjgaardDepartment of Cardiothoracic Intensive Care Unit Odense University Hospital Odense Denmark.
Christian HassagerDepartment of Cardiology, The Heart Centre Copenhagen University Hospital Copenhagen Denmark.ORCID 0000-0002-1199-0981

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the management of patients resuscitated from out-of-hospital cardiac arrest, a primary goal is to restore sufficient oxygen delivery (DO METHODS AND

resultsThis post hoc analysis of the BOX (Blood Pressure and Oxygen Targets) study included adult patients who were comatose and experienced out-of-hospital cardiac arrest from a presumed cardiac cause, who were randomized to a mean arterial blood pressure (MAP) target of 63 mm Hg (MAP63) or 77 mm Hg (MAP77) and a Restrictive PaO

conclusionsTargeting a MAP of 77 mm Hg resulted in an overall increase in DO

Indexed as

ComaOut-of-Hospital Cardiac ArrestOxygenOxygen ConsumptionAgedArterial PressureBlood PressureCardiopulmonary ResuscitationFemaleHumansMaleMiddle AgedTime FactorsTreatment OutcomeOxygenblood pressureFick's principlehemoglobinout‐of‐hospital cardiac arrestoxygen consumptionoxygen deliveryoxygen supply

Identifiers

PMID39435704
PMCPMC11935676

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.