Evidence map›Paper›PMID 39440794›Full record

ArticleFly2024

Mifepristone and rapamycin have non-additive benefits for life span in mated female

Gary N Landis, Britta Baybutt, Shoham Das, Yijie Fan, Kate Olsen, Karissa Yan, John Tower

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Fly, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Machine Learning Scoring Reveals Increased Frequency of Falls Proximal to Death in Drosophila melanogaster.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gary N LandisMolecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA.
Britta BaybuttMolecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA.
Shoham DasMolecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA.
Yijie FanMolecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA.
Kate OlsenMolecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA.
Karissa YanMolecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA.
John TowerMolecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA.

Funding

NIA NIH HHS R01 AG057741
6 · The paper itself

Abstract

The drugs mifepristone and rapamycin were compared for their relative ability to increase the life span of mated female

Indexed as

Drosophila melanogasterLongevityMifepristoneSirolimusAnimalsFemaleMitophagyMifepristoneSirolimusageingDrosophilahypertrophymidgutmifepristonemitophagyplasticityrapamycinsex peptidesteroid

Identifiers

PMID39440794
PMCPMC11514543

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.