Evidence map›Paper›PMID 39443318›Full record

ArticleUrolithiasis2024

Association between remnant cholesterol and risk of kidney stones: a case-control study in Chinese adults.

Dawei Wang, Feng Shi, Dingguo Zhang, Hui Wang, Wensun Chen, Zijian Zhou

Abstract read
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In one paragraph

Article in Urolithiasis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dawei Wang *Department of Urology, School of Medicine, Ruijin Hospital, Shanghai Jiao Tong University, Shanghai, 200040, China.
Feng Shi *CAAC East China Aviation Personnel Medical Appraisal Center, Civil Aviation Shanghai Hospital, Shanghai, 200040, China.
Dingguo ZhangDepartment of Urology, Shanghai Pudong New Area people's Hospital, Shanghai, 200040, China.
Hui WangDepartment of Urology, Shanghai Anting Hospital, Shanghai, 200040, China.
Wensun ChenDepartment of Urology, Huashan Hospital, Fudan University, Shanghai, 200040, China. 23111220060@m.fudan.edu.cn.
Zijian ZhouDepartment of Urology, Huashan Hospital, Fudan University, Shanghai, 200040, China. zjzhou21@m.fudan.edu.cn.

Funding

The research is funded by the China Civil Aviation Administration Research Project No. 254
6 · The paper itself

Abstract

Remnant cholesterol (RC), a key indicator of dyslipidemia, has been validated as a contributing factor to metabolic and cardiovascular diseases, both of which are closely associated with kidney stones (KS). This study aimed to investigate the association between RC and the risk of KS in Chinese adults. A total of 8,576 KS cases (mean age 55.87, 69.37% male) and 137,523 controls (mean age 54.57, 51.62% male) were included in this case-control study. RC was calculated using the formula: RC = TC-HDL-LDL. KS was ascertained with ultrasound by well-trained physicians. Multivariable logistic and restricted cubic spline (RCS) were applied to investigate the relationship between RC and KS. A total of 146,099 subjects (weighted mean age 54.64 years and 52.66% male) were included with mean RC = 0.8 for controls and RC = 0.72 for KS cases (P < 0.001). The multivariable-adjusted OR for KS occurrence across consecutive quartiles was 1.00 (reference), 1.05 (0.98-1.12), 1.15 (1.07-1.22), and 1.44 (1.35-1.53), respectively. Moreover, each standard deviation increment of RC was associated with a 15% (OR:1.15, 95% CI: 1.12-1.19) higher risk of KS occurrence. RCS showed significant and linear dose-response relationships between RC and KS occurrence (P-overall < 0.001, P-nonlinear = 0.270). The positive associations between RC and KS risk persisted in sensitivity analyses, suggesting the robustness of the results. In this case-control study of Chinese adults, elevated RC was associated with the occurrence of KS.

Indexed as

CholesterolKidney CalculiAdultAgedCase-Control StudiesChinaEast Asian PeopleFemaleHumansMaleMiddle AgedRisk AssessmentRisk FactorsCholesterolCase-control studyChinese adultsDyslipidemiaKidney stoneRemnant cholesterol

Identifiers

PMID39443318

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.