Evidence map›Paper›PMID 39443499›Full record

ArticleScientific reports2024

Genetic variation, structural analysis, and virulence implications of BimA and BimC in clinical isolates of Burkholderia pseudomallei in Thailand.

Charlene Mae Salao Cagape, Rathanin Seng, Natnaree Saiprom, Sarunporn Tandhavanant, Claire Chewapreecha, Usa Boonyuen, T Eoin West, Narisara Chantratita

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Charlene Mae Salao CagapeDepartment of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Rathanin SengDepartment of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Natnaree SaipromDepartment of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Sarunporn TandhavanantDepartment of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Claire ChewapreechaMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Usa BoonyuenDepartment of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
T Eoin WestDivision of Pulmonary, Critical Care & Sleep Medicine, Department of Medicine, University of Washington, Seattle, WA, USA.
Narisara ChantratitaDepartment of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand. narisara@tropmedres.ac.

Funding

Determinants of Outcome and Recurrent Infections in MelioidosisU01AI115520 · NIAID · MAHIDOL UNIVERSITY · PI CHANTRATITA, NARISARA, WEST, TIMOTHY EOIN · 2015 to 2019
$2.0M
National Institute of Allergy and Infectious Diseases of the National Institutes of Health U01AI115520NIAID NIH HHS U01 AI115520The German Academic Exchange Service: Deutscher Akademischer Austauschdienst (DAAD) and SEAMEO TropMed Network 91777149Wellcome TrustWellcome Trust 220211
6 · The paper itself

Abstract

Melioidosis is a life-threatening tropical disease caused by an intracellular gram-negative bacterium Burkholderia pseudomallei. B. pseudomallei polymerizes the host cell actin through autotransporters, BimA, and BimC, to facilitate intracellular motility. Two variations of BimA in B. pseudomallei have been reported previously: BimA

Indexed as

Burkholderia pseudomalleiGenetic VariationMelioidosisA549 CellsBacterial ProteinsGenome, BacterialHumansMicrofilament ProteinsPhylogenyThailandVirulenceBacterial ProteinsBimA protein, Burkholderia pseudomalleiMicrofilament ProteinsActin-based motilityBimABimCBurkholderia pseudomalleiMelioidosisVariation

Identifiers

PMID39443499
PMCPMC11499645

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.