Evidence map›Paper›PMID 39444286›Full record

ArticleRenal failure2024

Second transplantation after kidney graft loss in primary hyperoxaluria type 2: a pedigree study and mutation analysis.

Yushi Peng, Yingchun Zheng, Fu Xiong, Mingming Zhang, Yuchen Wang, Jia Luo, Wenli Zeng, Jialiang Hui, Wenfeng Deng, Jian Xu and 3 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Renal failure, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yushi PengDepartment of Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Yingchun ZhengDepartment of Prenatal Diagnostic Center, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.ORCID 0000-0001-7902-6307
Fu XiongDepartment of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.ORCID 0000-0003-2428-6165
Mingming ZhangDepartment of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Yuchen WangDepartment of Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Jia LuoDepartment of Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Wenli ZengDepartment of Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Jialiang HuiDepartment of Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Wenfeng DengDepartment of Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Jian XuDepartment of Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Yun MiaoDepartment of Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Renfei XiaDepartment of Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Yiling FangDepartment of Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou, China.ORCID 0000-0002-1471-0287

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrimary hyperoxaluria type 2 (PH2) is a rare disorder caused by

methodsWe report a case of PH2 with a three-generational pedigree. The

resultsThe proband underwent her first kidney transplantation in 2015, and experienced recurrent urinary tract infections and urolithiasis postoperatively. Graft failure occurred in 2018. Whole exome sequencing identified compound heterozygous

conclusionsOur findings suggest that treatment strategies for the long-term prevention of oxalate nephropathy should be developed for patients with PH2 receiving isolated kidney transplantation. Moreover, the pathogenicity of the compound heterozygous

Indexed as

Hyperoxaluria, PrimaryKidney TransplantationMutationPedigreeAdultAlcohol OxidoreductasesDNA Mutational AnalysisHumansReoperationAlcohol Oxidoreductasesglyoxylate reductasefunctional analysisGRHPRkidney transplantationmutationpedigreeprimary hyperoxaluria type 2

Identifiers

PMID39444286
PMCPMC11504218

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.