ArticleJournal of diabetes investigation2025
Association of impaired fasting glucose with cardiometabolic multimorbidity: The Kailuan study.
Article in Journal of diabetes investigation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Article
- Residual inflammatory risk as a predictor of cardiometabolic multi-morbidity: results from three prospective cohorts.Journal of health, population, and nutrition · 2026Article
- Prediabetes and stroke risk in U.S. adults: a machine learning-based analysis with causal mediation insights.Diabetology & metabolic syndrome · 2026Article
- The association between coronary microvascular dysfunction and HbA1c in patients with unstable angina pectoris.Frontiers in cardiovascular medicine · 2026Article
- Nonlinear association between glycemic markers and incident cardio‑renal‑metabolic multimorbidity: two decades of follow‑up in the Tehran Lipid and Glucose Study.American journal of preventive cardiology · 2025Article
- Identifying metabolic parameters as key indicators of hyperuricemia and ischemic stroke comorbidity via interpretable Clinlabomics models.Frontiers in endocrinology · 2025Article
- Elevated mean arterial pressure and risk of impaired fasting glucose: a multicenter cohort study revealing age and sex interactions.Frontiers in endocrinology · 2025Article
- The predictive value of hsCRP/HDL-C ratio for cardiometabolic multimorbidity in middle-aged and elderly people: evidence from a large national cohort study.Frontiers in nutrition · 2025Article
- A study on predicting impaired fasting glucose risk in Chinese adults based on individual characteristics.Frontiers in medicine · 2025Article
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7 authors.
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Abstract
AIMS/
introductionWe investigated the association between impaired fasting glucose (IFG) and cardiometabolic multimorbidity (CMM) in the Chinese population. MATERIALS AND
methodsWe included 119,368 participants, free of diabetes mellitus and cardiovascular disease, who participated in the health examination (2006, 2008, 2010) of the Kailuan Study. According to World Health Organization diagnostic criteria, participants were divided into normal fasting blood glucose (FBG) (<6.1 mmol/L) and IFG (FBG 6.1-6.9 mmol/L) groups. CMM was defined as having two or more cardiometabolic diseases, including myocardial infarction, stroke and diabetes mellitus. We used Cox proportional hazards models to evaluate associations between IFG and CMM.
resultsDuring a median follow-up period of 13.94 years, 2,432 CMM incident events occurred. After adjusting potential confounders, the hazard ratio (HR) and 95% confidence interval (CI) for CMM in the IFG group was 2.83 (95% CI 2.58-3.10) versus the normal FBG group. The HR of IFG for diabetes mellitus was 3.43 (95% CI 3.30-3.55), which was >1.25 (95% CI 1.13-1.37) for myocardial infarction, 1.16 (95% CI 1.07-1.25) for ischemic stroke and 1.06 (95% CI 0.88-1.27) for hemorrhagic stroke. Compared with normal FBG, HRs for risk of IFG for CMM were 2.73 (95% CI 2.48-3.02) in men and 3.86 (95% CI 2.92-5.09) in women.
conclusionIFG was a risk factor for CMM. The effect of IFG on diabetes mellitus was stronger than that on other cardiometabolic diseases. The effects of IFG for CMM differed by sex.
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