Evidence mapPaperPMID 39447046Full record

ReviewJNCI cancer spectrum2024

Narrative review of lifestyle interventions in breast cancer survivors: current evidence and future directions.

Kelsey Gabel, Kaitlin Chakos, Manoela Lima Oliveira, Julienne Sanchez Perez, Kate Cares, Natalia Salvatierra Lima, Pamela Ganschow, Betina Yanez, Vijayakrishna Gadi, Lisa Tussing-Humphreys

Abstract readReview
In one paragraph

Review in JNCI cancer spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Biochemical landscape of breast cancer: integrating serum markers with clinical prognosis and staging.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
  3. Article
  4. Reply to Braillon.JNCI cancer spectrum · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Kelsey GabelDepartment of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, IL 60612, United States.ORCID 0000-0003-4613-8892
Kaitlin ChakosDepartment of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, IL 60612, United States.ORCID 0009-0001-0887-4277
Manoela Lima OliveiraDepartment of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, IL 60612, United States.ORCID 0000-0002-6751-0684
Julienne Sanchez PerezDepartment of Medicine, University of Illinois at Chicago, Chicago, IL 60612, United States.ORCID 0009-0001-6285-1607
Kate CaresDepartment of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, IL 60612, United States.ORCID 0000-0001-5382-1409
Natalia Salvatierra LimaDepartment of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, IL 60612, United States.ORCID 0000-0001-9430-1557
Pamela GanschowUniversity of Illinois Cancer Center, Chicago, IL 60612, United States.
Betina YanezNorthwestern Medicine Feinberg School of Medicine, Chicago, IL 60611, United States.ORCID 0000-0003-1503-0600
Vijayakrishna GadiUniversity of Illinois Cancer Center, Chicago, IL 60612, United States.ORCID 0009-0001-6272-8844
Lisa Tussing-HumphreysDepartment of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, IL 60612, United States.ORCID 0009-0005-5727-9502

Funding

Mediterranean Diet and Weight Loss: Targeting the Bile Acid/Gut Microbiome Axis to Reduce Colorectal Cancer RiskR01CA250390 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · 2022 to 2025
$1.9M
UIC Building Interdisciplinary Research Careers in Women's Health ProgramK12AR084225 · UNIVERSITY OF ILLINOIS AT CHICAGO · 2025 to 2025
$907k
NCI NIH HHS L30 CA295383NIAMS NIH HHS K12 AR084225NIH HHS R01CA250390
6 · The paper itself

Abstract

backgroundIn 8 females, 1 will be diagnosed with breast cancer in their lifetime. Although medical advances have increased the likelihood of survival, up to 90% of females will gain weight during and after treatment increasing the risk of breast cancer recurrence and obesity-related comorbidities in survivorship. Behavioral lifestyle interventions focused on diet with or without physical activity can provide breast cancer survivors nonpharmacological options to decrease weight gain and cardiometabolic risk.

methodA PubMed search was conducted to identify all behavioral lifestyle interventions focused on diet or diet combined with physical activity longer than 4 weeks of duration in breast cancer survivors that included body weight as an outcome. This review aims to summarize the effects on body weight, body composition, and cardiometabolic risk markers.

resultsThe review shows there is high heterogeneity in type and duration of the intervention to affect weight and cardiometabolic risk in survivorship. Calorie restriction with and without physical activity appears to promote weight loss among breast cancer survivors. However, the effects on cardiometabolic factors are less clear.

conclusionsFuture studies should be powered for body weight and cardiometabolic effects. Researchers should also consider interventions that (1) are less complex, (2) recruit a more racially and ethnically diverse sample, (3) integrate resistance training, (4) implement the intervention in closer proximity to diagnosis, (5) target weight management in this population before it occurs, and (6) analyze body composition in addition to body weight measurements.

Indexed as

Body CompositionBreast NeoplasmsCancer SurvivorsExerciseLife StyleBody WeightCaloric RestrictionCardiometabolic Risk FactorsDietFemaleHumansObesityResistance TrainingWeight GainWeight Loss

Identifiers

PMID39447046
PMCPMC11631304

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.