Evidence mapPaperPMID 39448410Full record

ArticleCanadian journal of anaesthesia = Journal canadien d'anesthesie2024

Use of opioids and opioid alternatives during general anesthesia: a pan-Canadian survey among anesthesiologists.

Michael Verret, Manoj M Lalu, Alexandre Assi, Stuart G Nicholls, Alexis F Turgeon, Francois M Carrier, Daniel I McIsaac, Ian Gilron, Fiona Zikovic, Megan Graham and 7 more

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Article in Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Michael VerretDepartment of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Université Laval, Quebec City, QC, Canada. michael.verret.med@ssss.gouv.qc.ca.ORCID 0000-0003-3257-7878
Manoj M LaluClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Alexandre AssiSchool of Medicine, Trinity College Dublin, Dublin, Ireland.
Stuart G NichollsClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Alexis F TurgeonDepartment of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Université Laval, Quebec City, QC, Canada.
Francois M CarrierDepartment of Anesthesiology, Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada.
Daniel I McIsaacClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Ian GilronDepartment of Anesthesiology and Perioperative Medicine, Queen's University, Kingston, ON, Canada.
Fiona ZikovicPatient Partner, The Ottawa Hospital, Ottawa, ON, Canada.
Megan GrahamPatient Partner, The Ottawa Hospital, Ottawa, ON, Canada.
Maxime LêPatient Partner, The Ottawa Hospital, Ottawa, ON, Canada.
Allison GeistPatient Partner, The Ottawa Hospital, Ottawa, ON, Canada.
Guillaume MartelClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Jason A McVicarClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Husein MolooClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Dean FergussonClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Canadian Perioperative Anesthesia Clinical Trials (PACT) group

Funding

Non-US Government Research Support
6 · The paper itself

Abstract

purposeWhile there is limited patient-centred evidence (i.e., evidence that is important for patients and end-users) to inform the use of pharmacologic opioid minimization strategies (i.e., the use of opioid alternatives) for adult surgical patients requiring general anesthesia, such strategies are increasingly being adopted into practice. Our objectives were to describe anesthesiologists' beliefs regarding intraoperative opioid minimizing strategies use and utility, and to explore important clinical decision-making factors.

methodsWe conducted a pan-Canadian web-based survey of anesthesiologists that was distributed using a modified Dillman technique. Our multidisciplinary team, including a patient partners panel, participated in the process of domains and items generation, items reduction, formatting, and composition. Our sampling frames were members of the Canadian Anesthesiologists' Society and members of the Association des Anesthésiologistes du Québec. We used the newsletters of each organization to distribute our survey, which was available in English and French and housed on the LimeSurvey (LimeSurvey GmbH, Hamburg, Germany) platform.

resultsFrom our eligible sampling frame, 18% completed the survey (356 respondents out of 2,008 eligible participants). Most of the respondents believed that using opioid minimization strategies during general anesthesia could improve postoperative clinical outcomes, including pain control (84% agree or strongly agree, n = 344/409). Reported use of pharmacologic opioid minimization strategies was variable; however, most respondents believed that nonsteroidal anti-inflammatory drugs, acetaminophen, N-methyl-D-aspartate receptor antagonists (ketamine), α

conclusionIn our survey of Canadian anesthesiologists, several opioid minimization strategies were believed to be effective complements to general anesthesia, although there was substantial variation in their reported use. Future randomized controlled trials and systematic reviews evaluating the effectiveness of opioid minimization strategies should prioritize patient-centred outcome measures assessment such as the quality of recovery or the impact of acute pain on functioning.

Indexed as

Analgesics, OpioidAnesthesia, GeneralAnesthesiologistsAdultCanadaClinical Decision-MakingFemaleHumansMaleMiddle AgedPostoperative PainPractice Patterns, Physicians'Surveys and QuestionnairesAnalgesics, Opioidanesthesiologyopioid alternativesopioidspatient engagementsurvey

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.