Evidence map›Paper›PMID 39449145›Full record

ArticleBMC chemistry2024

Design, synthesis, and biological investigations of new pyrazole derivatives as VEGFR2/CDK-2 inhibitors targeting liver cancer.

Manar G Salem, Mohamed S Nafie, Aya A Elzamek, Hosam A Elshihawy, Mamdouh A Sofan, Elham Negm

Abstract read
In one paragraph

Article in BMC chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Manar G SalemPharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Suez Canal University, Ismailia, P.O. 41522, Egypt. manar.galal@pharm.suez.edu.eg.
Mohamed S NafieDepartment of Chemistry, College of Sciences, University of Sharjah, P.O. 27272, Sharjah, United Arab Emirates.
Aya A ElzamekPharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Suez Canal University, Ismailia, P.O. 41522, Egypt.
Hosam A ElshihawyPharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Suez Canal University, Ismailia, P.O. 41522, Egypt.
Mamdouh A SofanDepartment of Chemistry, Faculty of Science, Damietta University, New Damietta, Egypt.
Elham NegmDepartment of Chemistry, Faculty of Science, Damietta University, New Damietta, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New Series of N-Manniche bases 3,4 (a-c) and 5,6 (a-b) were synthesized through the reaction of benzaldehyde and amine with 3-methyl-4-(aryldiazenyl)-1H-pyrazol-5-ol derivatives 2(a-c), they were fully characterized by FT-IR, (

Indexed as

Anti-cancer activityCDK-2 kinase activitiesMolecular dockingPyrazoleVEGFR2

Identifiers

PMID39449145
PMCPMC11520136

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.