ArticleAndrology2025
Healthy and unhealthy dietary patterns and sperm quality from the Led-Fertyl study.
Article in Andrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Health and Environmental Impacts, Safety, and Affordability of the EAT-Lancet Planetary Health Diet: A Multidisciplinary Systematic Review and Meta-Analysis.Advances in nutrition (Bethesda, Md.) · 2026Pooled it
- Nut Consumption and Sperm Quality in Healthy Men: Results From the Led-Fertyl Study.Andrology · 2026Article
- From fork to fatherhood: Unveiling the link between dietary pattern indices and biochemical parameters of semen.PloS one · 2026Article
- Article
- Life's Essential 8 score and its association with sperm quality parameters in reproductive-aged men: evidence from the Led-Fertyl cohort.Human reproduction open · 2025Article
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11 authors.
Funding
Abstract
backgroundDietary patterns may affect sperm quality, but the scientific evidence is limited.
objectiveTo evaluate the association between adherence to different a-priori dietary patterns and sperm quality parameters in healthy reproductive-age men. MATERIALS AND
methodsA cross-sectional analysis was conducted using data from 200 young men enrolled in the Led-Fertyl study. Tertiles of six a-priori dietary patterns were estimated: four healthy dietary patterns [Mediterranean Diet Adherence Screener (MEDAS), Dietary Approaches to Stop Hypertension (DASH), Healthful Plant-Based Diet Index (hPDI) and EAT-Lancet Score], and two unhealthy dietary patterns [Western Diet and Unhealthful Plant-Based Diet Index (uPDI)]. Sperm quality parameters (count, concentration, vitality, total and progressive motility, and normal morphology) were considered the main outcomes.
resultsCompared with the lowest tertile, participants in the highest MEDAS tertile had higher total sperm count (β = 3.2;95%CI: 1.0, 5.5) and concentration (β = 1.8;95%CI: 0.6, 3.0), and total (β = 8.2;95%CI: 1.3, 15.1) and progressive motility (β = 7.1;95%CI: 0.2, 14.0). Similarly, participants in the highest hPDI tertile had higher total sperm count (β = 3.4;95%CI: 1.4, 5.5) and concentration (β = 1.2;95%CI: 0.0, 2.3) compared with those in the lowest tertile. When these dietary patterns were modelled as continuous variables (for each 1-point increment in the specific score), an inverse association was found between the uPDI and Western and total sperm count [(β = -2.7;95%CI: -4.8, -0.7) and (β = -3.8;95%CI: -5.8, -1.7), respectively] and sperm concentration [(β = -1.2;95%CI: -2.4, -0.1) and (β = -1.7;95%CI: -2.8, -0.5), respectively]. Compared with participants in the lowest tertile, those in the highest uPDI tertile presented higher odds of abnormal sperm concentration (OR: 4.6;95%CI: 1.0, 19.9) and one or more seminogram abnormalities (OR: 2.3;95%CI: 1.1, 5.0).
conclusionsOur findings suggest that higher adherence to healthy dietary patterns (Mediterranean and healthful plant-based diet) was positively associated with better sperm quality parameters, in contrast, greater adherence to unhealthy dietary patterns was inversely associated.
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