Evidence map›Paper›PMID 39451433›Full record

ReviewHealthcare (Basel, Switzerland)2024

Exploring the Link between Xerostomia and Oral Health in Mental Illness: Insights from Autism Spectrum Disorder, Depression, Bipolar Disorder, and Schizophrenia.

Rou-Jun Chen, Kuei-Hung Lai, Chun-Hung Lee, Hao-Ying Lin, Cheng-Chieh Lin, Chi-Hsiu Chen, Wei Chen, Wei-Yu Chen, Thi Thuy Tien Vo, I-Ta Lee

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Healthcare (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rou-Jun ChenSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110301, Taiwan.
Kuei-Hung LaiGraduate Institute of Pharmacognosy, College of Pharmacy, Taipei Medical University, Taipei 110301, Taiwan.ORCID 0000-0001-7220-6356
Chun-Hung LeeSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110301, Taiwan.
Hao-Ying LinSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110301, Taiwan.
Cheng-Chieh LinSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110301, Taiwan.
Chi-Hsiu ChenSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110301, Taiwan.
Wei ChenSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110301, Taiwan.
Wei-Yu ChenSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110301, Taiwan.
Thi Thuy Tien VoFaculty of Dentistry, Nguyen Tat Thanh University, Ho Chi Minh City 700000, Vietnam.
I-Ta LeeSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110301, Taiwan.ORCID 0000-0002-8451-0280

Funding

National Science and Technology Council of Taiwan NSTC 111-2320-B-038-040-MY3National Science and Technology Council of Taiwan NSTC 113-2321-B-255-001National Science and Technology Council of Taiwan NSTC 113-2628-B-038-009-MY3
6 · The paper itself

Abstract

backgroundThe relationship between mental disorders and oral health is complex, involving behavioral, biological, and psychosocial factors. This review aims to investigate the impact of mental disorders, including autism spectrum disorder (ASD), depression, bipolar disorder, and schizophrenia, on oral health outcomes.

methodsA comprehensive review of existing literature was conducted to analyze the oral health outcomes associated with each mental disorder. The focus was on examining dietary habits, oral hygiene behaviors, physiological changes, and medication side effects that contribute to oral health issues.

resultsThe findings indicate that individuals with ASD often exhibit unique dietary habits and reduced oral hygiene capabilities due to sensory sensitivities, leading to a higher prevalence of dental caries and periodontal diseases. Depression and bipolar disorder are associated with physiological changes such as reduced saliva production and poor oral hygiene behaviors, increasing the risk of oral health problems. Medications used for these conditions exacerbate issues like xerostomia, further elevating the risk of dental diseases. Schizophrenia poses additional challenges, including cognitive impairments and medication side effects that hinder effective oral care, heightening susceptibility to oral diseases.

conclusionsThis review highlights the specific oral health challenges associated with different mental disorders and emphasizes the need for tailored dental care strategies that integrate mental health considerations. The study contributes to the literature by demonstrating the unique oral health impacts of these disorders. However, the findings are limited by the scope of available cross-sectional data and the absence of longitudinal studies. Future research should focus on longitudinal and intervention-based studies to explore causal relationships and develop effective treatments.

Indexed as

autism spectrum disorderbipolar disorderdepressionmental disordersoral healthschizophrenia

Identifiers

PMID39451433
PMCPMC11507428

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.