Evidence map›Paper›PMID 39451776›Full record

ArticleCurrent oncology (Toronto, Ont.)2024

Exploring the Frequency and Risk Factors of Hyperprogressive Disease in Patients with Advanced Melanoma Treated with Immune Checkpoint Inhibitors.

Caner Acar, Haydar Çağatay Yüksel, Gökhan Şahin, Fatma Pinar Açar, Burçak Karaca

Abstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Caner AcarDivision of Medical Oncology, Departmant of Internal Medicine, Ege University Medical Faculty, 35100 Izmir, Turkey.ORCID 0000-0002-9782-6807
Haydar Çağatay YükselDivision of Medical Oncology, Departmant of Internal Medicine, Ege University Medical Faculty, 35100 Izmir, Turkey.ORCID 0000-0001-8857-2983
Gökhan ŞahinDivision of Medical Oncology, Departmant of Internal Medicine, Ege University Medical Faculty, 35100 Izmir, Turkey.ORCID 0000-0003-1478-9383
Fatma Pinar AçarDivision of Medical Oncology, Departmant of Internal Medicine, Ege University Medical Faculty, 35100 Izmir, Turkey.
Burçak KaracaDivision of Medical Oncology, Departmant of Internal Medicine, Ege University Medical Faculty, 35100 Izmir, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperprogressive disease (HPD) is described as the unexpected rapid growth of a tumour accompanied by a decline in performance status. While immune checkpoint inhibitors (ICIs) have improved outcomes in advanced melanoma, HPD remains a significant challenge in a subset of patients. Although HPD has been extensively studied in various solid tumours, research specifically focusing on advanced melanoma remains limited. We analysed 158 advanced melanoma patients, with 66.5% (

Indexed as

Immune Checkpoint InhibitorsMelanomaAdultAgedAged, 80 and overDisease ProgressionFemaleHumansIpilimumabMaleMiddle AgedNivolumabRisk FactorsImmune Checkpoint InhibitorsIpilimumabNivolumabadvanced melanomahyperprogressive diseaseimmune checkpoint inhibitorsoverall survivalrisk factors

Identifiers

PMID39451776
PMCPMC11505979

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.