Evidence map›Paper›PMID 39452749›Full record

ArticlePathogens (Basel, Switzerland)2024

Differential Regulation of L-Arginine Metabolism through NOS2 and Arginases during Infection with

Arturo A Wilkins-Rodríguez, Paz María Salazar-Schettino, Rebeca G Manning-Cela, Laila Gutiérrez-Kobeh

Abstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Arturo A Wilkins-RodríguezUnidad de Investigación UNAM-INC, División de Investigación, Facultad de Medicina, Universidad Nacional Autónoma de México-Instituto Nacional de Cardiología "Ignacio Chávez", Mexico City 14080, Mexico.
Paz María Salazar-SchettinoLaboratorio de Biología de Parásitos, Departamento de Microbiología y Parasitología, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.ORCID 0000-0001-8490-5293
Rebeca G Manning-CelaDepartamento de Biomedicina Molecular, Centro de Investigación y de Estudios Avanzados del IPN, Mexico City 07360, Mexico.
Laila Gutiérrez-KobehUnidad de Investigación UNAM-INC, División de Investigación, Facultad de Medicina, Universidad Nacional Autónoma de México-Instituto Nacional de Cardiología "Ignacio Chávez", Mexico City 14080, Mexico.ORCID 0000-0002-4414-6437

Funding

Dirección General de Asuntos del Personal Académico IN218119 and IN214522
6 · The paper itself

Abstract

L-arginine metabolism through arginases and inducible nitric oxide synthase (NOS2) constitutes a fundamental axis for the resolution or progression of Chagas disease. Infection with

Indexed as

ArginaseArginineChagas DiseaseMacrophagesNitric Oxide Synthase Type IITrypanosoma cruziAnimalsMiceMyocytes, CardiacArginaseArginineNitric Oxide Synthase Type IINos2 protein, mousearginases 1 and 2cardiomyocytesL-argininemacrophagesNOS2Trypanosoma cruzi

Identifiers

PMID39452749
PMCPMC11510043

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.