Evidence mapPaperPMID 39452857Full record

ReviewMarine drugs2024

From Sea to Lab: Angiotensin I-Converting Enzyme Inhibition by Marine Peptides-Mechanisms and Applications.

Du-Min Jo, Fazlurrahman Khan, Seul-Ki Park, Seok-Chun Ko, Kyung Woo Kim, Dongwoo Yang, Ji-Yul Kim, Gun-Woo Oh, Grace Choi, Dae-Sung Lee and 1 more

Abstract readReview
In one paragraph

Review in Marine drugs, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  3. Review
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  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Du-Min JoNational Marine Biodiversity of Korea (MABIK), Seochun 33662, Republic of Korea.
Fazlurrahman KhanOcean and Fisheries Development International Cooperation Institute, Pukyong National University, Busan 48513, Republic of Korea.ORCID 0000-0002-4902-3188
Seul-Ki ParkSmart Food Manufacturing Project Group, Korea Food Research Institute, Wanju 55365, Republic of Korea.
Seok-Chun KoNational Marine Biodiversity of Korea (MABIK), Seochun 33662, Republic of Korea.
Kyung Woo KimNational Marine Biodiversity of Korea (MABIK), Seochun 33662, Republic of Korea.ORCID 0000-0003-0503-9249
Dongwoo YangNational Marine Biodiversity of Korea (MABIK), Seochun 33662, Republic of Korea.
Ji-Yul KimNational Marine Biodiversity of Korea (MABIK), Seochun 33662, Republic of Korea.
Gun-Woo OhNational Marine Biodiversity of Korea (MABIK), Seochun 33662, Republic of Korea.
Grace ChoiNational Marine Biodiversity of Korea (MABIK), Seochun 33662, Republic of Korea.ORCID 0000-0002-8009-8006
Dae-Sung LeeNational Marine Biodiversity of Korea (MABIK), Seochun 33662, Republic of Korea.ORCID 0000-0003-0627-1402
Young-Mog KimDepartment of Food Science and Technology, Pukyong National University, Busan 48513, Republic of Korea.ORCID 0000-0002-2465-8013

Funding

National Marine Biodiversity Institute of Korea 2024M00500
6 · The paper itself

Abstract

To reveal potent ACE inhibitors, researchers screen various bioactive peptides from several sources, and more attention has been given to aquatic sources. This review summarizes the recent research achievements on marine peptides with ACE-inhibitory action and application. Marine peptides are considered excellent bioactives due to their large structural diversity and unusual bioactivities. The mechanisms by which these marine peptides inhibit ACE include competitive binding to ACEs' active site, interfering with ACE conformational changes, and avoiding the identification of substrates. The unique 3D attributes of marine peptides confer inhibition advantages toward ACE activity. Because IC

Indexed as

Angiotensin-Converting Enzyme InhibitorsAquatic OrganismsPeptidesAnimalsHumansPeptidyl-Dipeptidase AAngiotensin-Converting Enzyme InhibitorsPeptidesPeptidyl-Dipeptidase AACE inhibitorsantihypertensive activitycardiovascular diseasesmarine peptidesmechanism of actionmolecular interactionsstructural diversitytherapeutic potential

Identifiers

PMID39452857
PMCPMC11509120

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.