Evidence map›Paper›PMID 39455650›Full record

ArticleScientific reports2024

Effects of Lactiplantibacillus plantarum CBT LP3 and Bifidobacterium breve CBT BR3 supplementation on weight loss and gut microbiota of overweight dogs.

Jihee Choi, Dooheon Son, Subin An, Eunbee Cho, Sanghyun Lim, Hae-Jeung Lee

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Journal of microbiology and biotechnology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jihee ChoiDepartment of Food and Nutrition, College of Bionanotechnology, Gachon University, Seongnam-si, Gyeonggi-do, 13120, Republic of Korea.
Dooheon SonR&D Center, Cell Biotech Co. Ltd., Gimpo-si, Gyeonggi-do, 10003, Republic of Korea.
Subin AnDepartment of Food and Nutrition, College of Bionanotechnology, Gachon University, Seongnam-si, Gyeonggi-do, 13120, Republic of Korea.
Eunbee ChoR&D Center, Cell Biotech Co. Ltd., Gimpo-si, Gyeonggi-do, 10003, Republic of Korea.
Sanghyun LimR&D Center, Cell Biotech Co. Ltd., Gimpo-si, Gyeonggi-do, 10003, Republic of Korea. shlim@cellbiotech.com.
Hae-Jeung LeeDepartment of Food and Nutrition, College of Bionanotechnology, Gachon University, Seongnam-si, Gyeonggi-do, 13120, Republic of Korea. skysea1010@gmail.com.

Funding

The Korea Institute of Planning and Evaluation for Technology in Food, Agriculture, Forestry, and Fisheries funded by the Ministry of Agriculture, Food, and Rural Affairs 321036-05-1-HD040The Technology Development Program funded by the Ministry of SMEs and Startups (MSS, Korea) 00218423
6 · The paper itself

Abstract

The prevalence of obesity in dogs is increasing worldwide. This study evaluated the effects of a mixed probiotic formula on the weight, body condition score (BCS), blood metabolite profiles, and gut microbiota of overweight and obese dogs over a 12-week supplementation period to determine the anti-obesity effects of Lactiplantibacillus plantarum CBT LP3 and Bifidobacterium breve CBT BR3. This was a community-based, randomized study that sampled 41 overweight and obese dogs with a veterinarian-determined BCS of 6 or more. The physical activity of all the subjects was measured using a pedometer designed exclusively for dogs. The food intake was measured using the developed application. Only the treatment group received the mixed probiotic formula twice daily (3 g per dose). A significant decrease in body weight (p < 0.0001), BCS (p < 0.0001), serum TG (p < 0.0001), serum TC (p = 0.0400), and serum leptin (p = 0.0252), and a significantly increased serum adiponectin levels (p = 0.0007) were observed in the treatment group compared with the values in the control group. Microbiota analysis showed that Lactiplantibacillus increased and Erysipelatoclostridium, Staphylococcus, and Gemella decreased more significantly in the treatment group than in the control group. These results suggested that Lactiplantibacillus plantarum CBT LP3 and Bifidobacterium breve CBT BR3 may be effective in alleviating obesity in dogs.

Indexed as

Bifidobacterium breveDog DiseasesGastrointestinal MicrobiomeOverweightProbioticsAnimalsDietary SupplementsDogsFemaleLactiplantibacillus plantarumMaleObesityWeight LossBifidobacterium breve CBT BR3DogGut microbiotaLactiplantibacillus plantarum CBT LP3ObesityWeight

Identifiers

PMID39455650
PMCPMC11511819

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.