Evidence map›Paper›PMID 39456026›Full record

ArticleMolecular neurodegeneration2024

HDGFL2 cryptic protein: a portal to detection and diagnosis in neurodegenerative disease.

Ellen A Albagli, Anna Calliari, Tania F Gendron, Yong-Jie Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular neurodegeneration, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ellen A AlbagliDepartment of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
Anna CalliariDepartment of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
Tania F GendronDepartment of Neuroscience, Mayo Clinic, Jacksonville, FL, USA. gendron.tania@mayo.edu.
Yong-Jie ZhangDepartment of Neuroscience, Mayo Clinic, Jacksonville, FL, USA. zhang.yongjie@mayo.edu.ORCID http://orcid.org/0000-0002-2476-9565

Funding

Technology and Remote Assessment CoreU19AG063911 · NIA · MAYO CLINIC ROCHESTER · PI Adam Mark Staffaroni · 2019 to 2026
$120.9M
TDP-43 Loss-of-Function: Biology to BiomarkersP01AG019724 · NIA · UNIVERSITY OF PENNSYLVANIA · PI Jennifer Merrilees · 2002 to 2026
$67.2M
Research Education ComponentP30AG062677 · NIA · MAYO CLINIC ROCHESTER · PI KEJAL KANTARCI · 2019 to 2026
$33.5M
Project 3: Neuropathology of the multi-proteinopathy of c9FTD/ALS.P01NS084974 · NINDS · MAYO CLINIC JACKSONVILLE · PI PETRUCELLI, LEONARD · 2014 to 2024
$17.6M
Frontotemporal dementia and related disorders: transcriptomic profiling, biomarker discovery, and mechanistic insightR01NS121125 · NINDS · MAYO CLINIC JACKSONVILLE · PI GENDRON, TANIA FRANCE, VAN BLITTERSWIJK, MARKA · 2021 to 2025
$3.9M
Poly(ADP-ribose) promotes the condensation and toxicity of C9orf72 arginine-rich dipeptide repeat proteinsR01NS117461 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Tania France Gendron, Yongjie Zhang · 2021 to 2026
$2.9M
Double-stranded RNA in neuronal cell death in Alzheimer's and related neurodegenerative diseasesR01AG085307 · NIA · UNIVERSITY OF COLORADO · PI CHARLES A HOEFFER, Christopher D. Link · 2024 to 2026
$2.3M
Glycogen promotes protein aggregation in ALS and FTDR21NS127331 · NINDS · MAYO CLINIC JACKSONVILLE · PI ZHANG, YONGJIE · 2022 to 2022
$430k
NIA NIH HHS P01 AG019724NIA NIH HHS P30 AG062677NIA NIH HHS P30AG062677NIA NIH HHS R01 AG085307NIA NIH HHS R01AG085307NIA NIH HHS U19 AG063911NIA NIH HHS U19AG063911NINDS NIH HHS P01 NS084974NINDS NIH HHS P01NS084974NINDS NIH HHS R01 NS117461NINDS NIH HHS R01NS117461NINDS NIH HHS R01NS121125NINDS NIH HHS R21 NS127331NINDS NIH HHS R21NS127331Target ALS Target ALS
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Amyotrophic lateral sclerosisBiomarkersCerebrospinal fluidCryptic peptideFrontotemporal dementiaHepatoma derived growth factor 2NeurodegenerationTAR DNA-binding protein 43

Identifiers

PMID39456026
PMCPMC11515212

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.